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Cellosaurus MCF-7:2A (CVCL_4Y53)

[Text version]

Cell line name MCF-7:2A
Accession CVCL_4Y53
Resource Identification Initiative To cite this cell line use: MCF-7:2A (RRID:CVCL_4Y53)
Comments Caution: There is confusion in the literature between estrogen-independent MCF-7:2A (CVCL_4Y53), L-mimosine-resistant MCF-7/2a (CVCL_0412) and EREwtcluc transfected MCF-7-2a (CVCL_4Y54).
Sequence variations Homozygous for CDKN2A deletion (from parent cell line).
Heterozygous for PIK3CA p.Glu545Lys (c.1633G>A) (ClinVar=VCV000013655) (from parent cell line).
Disease Invasive ductal carcinoma, not otherwise specified (NCIt: C4194)
Derived from metastatic site: Pleural effusion.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0031 (MCF-7)
Sex of cell Female
Age at sampling 69Y
Category Cancer cell line
Publications

PubMed=7780972
Pink J.J., Jiang S.-Y., Fritsch M., Jordan V.C.
An estrogen-independent MCF-7 breast cancer cell line which contains a novel 80-kilodalton estrogen receptor-related protein.
Cancer Res. 55:2583-2590(1995)

Cross-references
Other Wikidata; Q54904399
Entry history
Entry creation14-Dec-2015
Last entry update02-Jul-2020
Version number8