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Cellosaurus HaCaT/SM (CVCL_4Z60)

[Text version]
Cell line name HaCaT/SM
Accession CVCL_4Z60
Resource Identification Initiative To cite this cell line use: HaCaT/SM (RRID:CVCL_4Z60)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI:25434; Bis(2-chloroethyl) sulfide (Sulfur mustard; Mustard agent).
Derived from site: In situ; Back, skin, epidermis; UBERON=UBERON_0001068+UBERON_0001003.
Cell type: Keratinocyte; CL=CL_0000312.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.His179Tyr (c.535C>T); ClinVar=VCV000127815; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg282Trp (c.843_844CC>TT); Zygosity=Heterozygous (from parent cell line).
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0038 (HaCaT)
Sex of cell Male
Age at sampling 62Y
Category Spontaneously immortalized cell line
Publications

PubMed=26463895; DOI=10.1016/j.toxlet.2015.09.023
Schmidt A., Steinritz D., Thiermann H.
Development of the sulfur mustard resistant keratinocyte cell line HaCaT/SM.
Toxicol. Lett. 244:44-48(2016)

Cross-references
Encyclopedic resources Wikidata; Q54872317
Entry history
Entry creation14-Dec-2015
Last entry update29-Jun-2023
Version number10