ID   HaCaT/SM
AC   CVCL_4Z60
DR   Wikidata; Q54872317
RX   PubMed=26463895;
CC   Population: Caucasian.
CC   Selected for resistance to: ChEBI; CHEBI:25434; Bis(2-chloroethyl) sulfide (Sulfur mustard; Mustard agent).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.His179Tyr (c.535C>T); ClinVar=VCV000127815; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg282Trp (c.843_844CC>TT); Zygosity=Heterozygous (from parent cell line).
CC   Derived from site: In situ; Back, skin, epidermis; UBERON=UBERON_0001068+UBERON_0001003.
CC   Cell type: Keratinocyte; CL=CL_0000312.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0038 ! HaCaT
SX   Male
AG   62Y
CA   Spontaneously immortalized cell line
DT   Created: 14-12-15; Last updated: 29-06-23; Version: 10
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RX   PubMed=26463895; DOI=10.1016/j.toxlet.2015.09.023;
RA   Schmidt A., Steinritz D., Thiermann H.;
RT   "Development of the sulfur mustard resistant keratinocyte cell line
RT   HaCaT/SM.";
RL   Toxicol. Lett. 244:44-48(2016).
//