Due to maintenance work, this service will suffer intermittent downtimes on Tuesday February 20th between 12.00 pm and 2.00 pm CEST.

Cellosaurus HEL/TGR (CVCL_4Z61)

Cell line name HEL/TGR
Accession CVCL_4Z61
Resource Identification Initiative To cite this cell line use: HEL/TGR (RRID:CVCL_4Z61)
Comments Selected for resistance to: ChEBI; CHEBI:90304; TG101209 (N-(tert-butyl)-3-((5-methyl-2-((4-(4-methylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)amino)benzenesulfonamide).
Derived from sampling site: Peripheral blood.
Disease Erythroleukemia (NCIt: C7152)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2481 (HEL 92.1.7)
Sex of cell Male
Category Cancer cell line

PubMed=21976548; DOI=10.1158/1078-0432.CCR-11-1541
Fiskus W., Verstovsek S., Manshouri T., Rao R., Balusu R., Venkannagari S., Rao N.N., Ha K., Smith J.E., Hembruff S.L., Abhyankar S., McGuirk J., Bhalla K.N.
Heat shock protein 90 inhibitor is synergistic with JAK2 inhibitor and overcomes resistance to JAK2-TKI in human myeloproliferative neoplasm cells.
Clin. Cancer Res. 17:7347-7358(2011)