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Cellosaurus SNU-1033 (CVCL_5002)

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Cell line name SNU-1033
Synonyms SNU1033
Accession CVCL_5002
Resource Identification Initiative To cite this cell line use: SNU-1033 (RRID:CVCL_5002)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: Seoul National University (SNU) cell line collection.
Population: Korean.
Doubling time: 42 hours (PubMed=10362137).
Microsatellite instability: Stable (MSS) (PubMed=10674020; PubMed=25926053).
Omics: Deep exome analysis.
Omics: Deep RNAseq analysis.
Omics: Transcriptome analysis.
Derived from sampling site: Rectum.
Sequence variations Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Heterozygous (PubMed=10362137; CCLE).
Mutation; HGNC; 11998; TP53; Simple; p.Pro190Leu (c.569C>T); ClinVar=VCV000418517; Zygosity=Homozygous (PubMed=10362137; CCLE).
Genome ancestry Source: PubMed=30894373

Origin% genome
Native American0
East Asian, North56.8
East Asian, South0
South Asian0
European, North0
European, South24.53
Disease Rectal adenocarcinoma (NCIt: C9383)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 45Y
Category Cancer cell line
STR profile Source(s): Genomics_Center_BCF_Technion; KCLB; PubMed=25926053

D3S135814,17 (KCLB)
17 (Genomics_Center_BCF_Technion)
D7S82011,12 (Genomics_Center_BCF_Technion; PubMed=25926053)
12 (KCLB)
Penta D11,12
Penta E11

Run an STR similarity search on this cell line

PubMed=10362137; DOI=10.1002/(SICI)1097-0215(19990611)81:6<902::AID-IJC11>3.0.CO;2-T
Oh J.-H., Ku J.-L., Yoon K.-A., Kwon H.-J., Kim W.-H., Park H.-S., Yeo K.-S., Song S.-Y., Chung J.-K., Park J.-G.
Establishment and characterization of 12 human colorectal-carcinoma cell lines.
Int. J. Cancer 81:902-910(1999)

PubMed=10674020; DOI=10.1016/S0959-8049(99)00206-3
Ku J.-L., Yoon K.-A., Kim D.-Y., Park J.-G.
Mutations in hMSH6 alone are not sufficient to cause the microsatellite instability in colorectal cancer cell lines.
Eur. J. Cancer 35:1724-1729(1999)

PubMed=19956504; DOI=10.4143/crt.2005.37.1.1
Ku J.-L., Park J.-G.
Biology of SNU cell lines.
Cancer Res. Treat. 37:1-19(2005)

PubMed=25926053; DOI=10.1038/ncomms8002
Medico E., Russo M., Picco G., Cancelliere C., Valtorta E., Corti G., Buscarino M., Isella C., Lamba S., Martinoglio B., Veronese S., Siena S., Sartore-Bianchi A., Beccuti M., Mottolese M., Linnebacher M., Cordero F., Di Nicolantonio F., Bardelli A.
The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets.
Nat. Commun. 6:7002-7002(2015)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3
Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. III, Barretina J., Gelfand E.T., Bielski C.M., Li H., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

Cell line collections KCLB; 01033
Cell line databases/resources CCLE; SNU1033_LARGE_INTESTINE
Cell_Model_Passport; SIDM00192
ColonAtlas; SNU1033
DepMap; ACH-000286
Biological sample resources BioSample; SAMN10987752
Chemistry resources PharmacoDB; SNU1033_1433_2019
Gene expression databases ArrayExpress; E-MTAB-2770
GEO; GSM1448078
Other Wikidata; Q54955088
Polymorphism and mutation databases Cosmic; 738855
Cosmic; 2612379
Cosmic; 2651858
IARC_TP53; 10837
LiGeA; CCLE_623
Entry history
Entry creation04-Apr-2012
Last entry update20-May-2021
Version number22