ID   SNU-1066
AC   CVCL_5005
SY   SNU1066
DR   BTO; BTO:0005924
DR   ArrayExpress; E-MTAB-2770
DR   BioSample; SAMN10987965
DR   Cell_Model_Passport; SIDM00170
DR   Cosmic; 934176
DR   DepMap; ACH-000682
DR   IARC_TP53; 11324
DR   KCLB; 01066
DR   LiGeA; CCLE_560
DR   PharmacoDB; SNU1066_1436_2019
DR   Wikidata; Q54955092
RX   PubMed=10369293;
RX   PubMed=19956504;
RX   PubMed=26589293;
RX   PubMed=31068700;
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Part of: Seoul National University (SNU) cell line collection.
CC   Population: Korean.
CC   Doubling time: 48 hours (PubMed=10369293).
CC   HLA typing: A*02:06,24:02; B*15:01,27:05; C*01:02,04:01 (PubMed=26589293).
CC   Sequence variation: Mutation; HGNC; 1787; CDKN2A; Simple; p.Asp92fs*54 (c.274delG); Zygosity=Homozygous (PubMed=10369293; DepMap).
CC   Sequence variation: Mutation; HGNC; 11730; TERT; Simple; c.1-146C>T (c.250C>T) (C250T); Zygosity=Unspecified; Note=In promoter (PubMed=31068700).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; c.514_559del46; Zygosity=Homozygous (PubMed=10369293; DepMap).
CC   Omics: Deep exome analysis.
CC   Omics: Transcriptome analysis by RNAseq.
CC   Derived from site: In situ; Larynx; UBERON=UBERON_0001737.
ST   Source(s): KCLB
ST   Amelogenin: X,Y
ST   CSF1PO: 11
ST   D13S317: 8,12
ST   D3S1358: 17
ST   D5S818: 9,11
ST   D7S820: 12
ST   FGA: 23
ST   TH01: 7,9
ST   TPOX: 8
ST   vWA: 17,18
DI   NCIt; C4044; Laryngeal squamous cell carcinoma
DI   ORDO; Orphanet_494550; Squamous cell carcinoma of the larynx
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   62Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 29-06-23; Version: 23
//
RX   PubMed=10369293; DOI=10.1097/00005537-199906000-00025;
RA   Ku J.-L., Kim W.-H., Lee J.-H., Park H.-S., Kim K.H., Sung M.-W.,
RA   Park J.-G.;
RT   "Establishment and characterization of human laryngeal squamous cell
RT   carcinoma cell lines.";
RL   Laryngoscope 109:976-982(1999).
//
RX   PubMed=19956504; DOI=10.4143/crt.2005.37.1.1;
RA   Ku J.-L., Park J.-G.;
RT   "Biology of SNU cell lines.";
RL   Cancer Res. Treat. 37:1-19(2005).
//
RX   PubMed=26589293; DOI=10.1186/s13073-015-0240-5;
RA   Scholtalbers J., Boegel S., Bukur T., Byl M., Goerges S., Sorn P.,
RA   Loewer M., Sahin U., Castle J.C.;
RT   "TCLP: an online cancer cell line catalogue integrating HLA type,
RT   predicted neo-epitopes, virus and gene expression.";
RL   Genome Med. 7:118.1-118.7(2015).
//
RX   PubMed=31068700; DOI=10.1038/s41586-019-1186-3;
RA   Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C.,
RA   McDonald E.R. III, Barretina J.G., Gelfand E.T., Bielski C.M., Li H.-X.,
RA   Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F.,
RA   Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R.,
RA   Lu Y.-L., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C.,
RA   Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A.,
RA   Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D.,
RA   Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L.,
RA   Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A.,
RA   Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D.,
RA   Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M.,
RA   Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R.,
RA   Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A.,
RA   Sellers W.R.;
RT   "Next-generation characterization of the Cancer Cell Line
RT   Encyclopedia.";
RL   Nature 569:503-508(2019).
//