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Cellosaurus SNU-1076 (CVCL_5006)

[Text version]

Cell line name SNU-1076
Synonyms SNU1076; NCI-SNU-1076
Accession CVCL_5006
Resource Identification Initiative To cite this cell line use: SNU-1076 (RRID:CVCL_5006)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: Seoul National University (SNU) cell line collection.
Doubling time: 36 hours (PubMed=10369293).
Omics: Deep exome analysis.
Omics: Deep RNAseq analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Sequence variations CDKN2A p.Pro114His (c.341C>A) (PubMed=10369293).
Heterozygous for PIK3CA p.His1047Arg (c.3140A>G) (CCLE).
Genome ancestry Source: PubMed=30894373

Origin% genome
African2.88
Native American0
East Asian, North66.81
East Asian, South28.32
South Asian0
European, North0
European, South1.99
Disease Laryngeal squamous cell carcinoma (NCIt: C4044)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 60Y
Category Cancer cell line
STR profile Source(s): KCLB

Markers:
AmelogeninX,Y
CSF1PO11,12
D3S135815
D5S8189,12
D7S82011,12
D13S3178,10
FGA24,25
TH016,7
TPOX8,11
vWA15,16

Run an STR similarity search on this cell line
Publications

PubMed=10369293; DOI=10.1097/00005537-199906000-00025
Ku J.-L., Kim W.-H., Lee J.-H., Park H.-S., Kim K.-H., Sung M.-W., Park J.-G.
Establishment and characterization of human laryngeal squamous cell carcinoma cell lines.
Laryngoscope 109:976-982(1999)

PubMed=19956504; DOI=10.4143/crt.2005.37.1.1
Ku J.-L., Park J.-G.
Biology of SNU cell lines.
Cancer Res. Treat. 37:1-19(2005)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3
Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. III, Barretina J., Gelfand E.T., Bielski C.M., Li H., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

Cross-references
Cell line collections KCLB; 01076
Cell line databases/resources CCLE; SNU1076_UPPER_AERODIGESTIVE_TRACT
Cell_Model_Passport; SIDM00168
DepMap; ACH-000549
Ontologies BTO; BTO:0005922
Biological sample resources BioSample; SAMN10988066
Gene expression databases ArrayExpress; E-MTAB-2770
GEO; GSM887603
GEO; GSM888686
Other Wikidata; Q54955093
Polymorphism and mutation databases Cosmic; 934177
IARC_TP53; 30157
LiGeA; CCLE_803
Entry history
Entry creation04-Apr-2012
Last entry updated05-Jul-2019
Version number17