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Cellosaurus SNU-1197 (CVCL_5016)

[Text version]

Cell line name SNU-1197
Synonyms SNU1197
Accession CVCL_5016
Resource Identification Initiative To cite this cell line use: SNU-1197 (RRID:CVCL_5016)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: Seoul National University (SNU) cell line collection.
Doubling time: 60 hours (PubMed=10362137).
Microsatellite instability: Stable (MSS) (PubMed=10674020).
Omics: Deep exome analysis.
Omics: Deep RNAseq analysis.
Sequence variations Heterozygous for APC p.Arg232Ter (c.694C>T) (CCLE).
Homozygous for KRAS p.Gly12Asp (c.35G>A) (ClinVar=VCV000012582) (PubMed=10362137; CCLE).
Homozygous for TP53 p.Arg175His (c.524G>A) (ClinVar=VCV000012374) (PubMed=10362137; CCLE).
Genome ancestry Source: PubMed=30894373

Origin% genome
African1.84
Native American0.35
East Asian, North62.22
East Asian, South34.04
South Asian0
European, North0
European, South1.55
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 70Y
Category Cancer cell line
STR profile Source(s): KCLB

Markers:
AmelogeninX
CSF1PO11,12
D3S135818
D5S81810,12
D7S82011,12
D13S3179,11
FGA23
TH018,9
TPOX7,8
vWA17

Run an STR similarity search on this cell line
Publications

PubMed=10362137; DOI=10.1002/(SICI)1097-0215(19990611)81:6<902::AID-IJC11>3.0.CO;2-T
Oh J.-H., Ku J.-L., Yoon K.-A., Kwon H.-J., Kim W.-H., Park H.-S., Yeo K.-S., Song S.-Y., Chung J.-K., Park J.-G.
Establishment and characterization of 12 human colorectal-carcinoma cell lines.
Int. J. Cancer 81:902-910(1999)

PubMed=10674020; DOI=10.1016/S0959-8049(99)00206-3
Ku J.-L., Yoon K.-A., Kim D.-Y., Park J.-G.
Mutations in hMSH6 alone are not sufficient to cause the microsatellite instability in colorectal cancer cell lines.
Eur. J. Cancer 35:1724-1729(1999)

PubMed=19956504; DOI=10.4143/crt.2005.37.1.1
Ku J.-L., Park J.-G.
Biology of SNU cell lines.
Cancer Res. Treat. 37:1-19(2005)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3
Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. III, Barretina J., Gelfand E.T., Bielski C.M., Li H., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

Cross-references
Cell line collections KCLB; 01197
Cell line databases/resources CCLE; SNU1197_LARGE_INTESTINE
Cell_Model_Passport; SIDM00171
ColonAtlas; SNU1197
DepMap; ACH-000412
Biological sample resources BioSample; SAMN10987710
Chemistry resources PharmacoDB; SNU1197_1443_2019
Gene expression databases ArrayExpress; E-MTAB-2770
Other Wikidata; Q54955105
Polymorphism and mutation databases Cosmic; 738859
Cosmic; 2612382
Cosmic; 2651861
IARC_TP53; 10840
LiGeA; CCLE_185
Entry history
Entry creation04-Apr-2012
Last entry update02-Jul-2020
Version number20