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Cellosaurus SNU-251 (CVCL_5040)

[Text version]

Cell line name SNU-251
Synonyms SNU251
Accession CVCL_5040
Resource Identification Initiative To cite this cell line use: SNU-251 (RRID:CVCL_5040)
Comments Part of: Seoul National University (SNU) cell line collection.
Doubling time: 46 hours (PubMed=9299249).
Sequence variations Hemizygous or homozygous for BRCA1 p.Trp1815Ter (c.5445G>A) (PubMed=9299249).
Heterozygous for MLH1 p.Ala723Asp (PubMed=9299249).
Disease BRCA1 syndrome (NCIt: C36100)
Ovarian endometrioid adenocarcinoma (NCIt: C7979)
Derived from metastatic site: Ascites.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 47Y
Category Cancer cell line
STR profile Source(s): KCLB; PubMed=22710073

Markers:
AmelogeninX
CSF1PO10,12
D2S133819,22
D3S135815,16
D5S81811
D7S82010,12
D8S117911,13
D13S3179
D16S53911
D18S5114,15
D19S43313.2,14.2
D21S1130,31.2
FGA20
TH018
TPOX12
vWA15,18

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Publications

PubMed=9299249; DOI=10.1006/gyno.1997.4785
Yuan Y., Kim W.-H., Han H.S., Lee J.-H., Park H.-S., Chung J.-K., Kang S.-B., Park J.-G.
Establishment and characterization of human ovarian carcinoma cell lines.
Gynecol. Oncol. 66:378-387(1997)

PubMed=19956504; DOI=10.4143/crt.2005.37.1.1
Ku J.-L., Park J.-G.
Biology of SNU cell lines.
Cancer Res. Treat. 37:1-19(2005)

PubMed=22710073; DOI=10.1016/j.ygyno.2012.06.017
Korch C., Spillman M.A., Jackson T.A., Jacobsen B.M., Murphy S.K., Lessey B.A., Jordan V.C., Bradford A.P.
DNA profiling analysis of endometrial and ovarian cell lines reveals misidentification, redundancy and contamination.
Gynecol. Oncol. 127:241-248(2012)

PubMed=23415752; DOI=10.1016/j.molonc.2012.12.007
Stordal B., Timms K., Farrelly A., Gallagher D., Busschots S., Renaud M., Thery J., Williams D., Potter J., Tran T., Korpanty G., Cremona M., Carey M.S., Li J., Li Y., Aslan O., O'Leary J.J., Mills G.B., Hennessy B.T.
BRCA1/2 mutation analysis in 41 ovarian cell lines reveals only one functionally deleterious BRCA1 mutation.
Mol. Oncol. 7:567-579(2013)

Cross-references
Cell line collections KCLB; 00251
Other Wikidata; Q54955155
Entry history
Entry creation04-Apr-2012
Last entry updated06-Sep-2019
Version number16