ID   SNU-251
AC   CVCL_5040
SY   SNU251
DR   cancercelllines; CVCL_5040
DR   KCLB; 00251
DR   Wikidata; Q54955155
RX   PubMed=9299249;
RX   PubMed=19956504;
RX   PubMed=22710073;
RX   PubMed=23415752;
CC   Part of: Seoul National University (SNU) cell line collection.
CC   Population: Korean.
CC   Doubling time: 46 hours (PubMed=9299249).
CC   Sequence variation: Mutation; HGNC; 1100; BRCA1; Simple; p.Trp1815Ter (c.5445G>A); ClinVar=VCV000055581; Zygosity=Homozygous or hemizygous (PubMed=9299249).
CC   Sequence variation: Mutation; HGNC; 7127; MLH1; Simple; p.Ala723Asp (c.2168C>A); Zygosity=Heterozygous (PubMed=9299249).
CC   Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
ST   Source(s): KCLB; PubMed=22710073
ST   Amelogenin: X
ST   CSF1PO: 10,12
ST   D13S317: 9
ST   D16S539: 11
ST   D18S51: 14,15
ST   D19S433: 13.2,14.2
ST   D21S11: 30,31.2
ST   D2S1338: 19,22
ST   D3S1358: 15,16
ST   D5S818: 11
ST   D7S820: 10,12
ST   D8S1179: 11,13
ST   FGA: 20
ST   TH01: 8
ST   TPOX: 12
ST   vWA: 15,18
DI   NCIt; C36100; BRCA1-associated hereditary breast and ovarian cancer syndrome
DI   NCIt; C7979; Ovarian endometrioid adenocarcinoma
DI   ORDO; Orphanet_145; Hereditary breast and ovarian cancer syndrome
DI   ORDO; Orphanet_454723; Endometrioid carcinoma of ovary
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   47Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 05-10-23; Version: 22
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RX   PubMed=9299249; DOI=10.1006/gyno.1997.4785;
RA   Yuan Y., Kim W.-H., Han H.S., Lee J.-H., Park H.-S., Chung J.-K.,
RA   Kang S.-B., Park J.-G.;
RT   "Establishment and characterization of human ovarian carcinoma cell
RT   lines.";
RL   Gynecol. Oncol. 66:378-387(1997).
//
RX   PubMed=19956504; DOI=10.4143/crt.2005.37.1.1;
RA   Ku J.-L., Park J.-G.;
RT   "Biology of SNU cell lines.";
RL   Cancer Res. Treat. 37:1-19(2005).
//
RX   PubMed=22710073; DOI=10.1016/j.ygyno.2012.06.017;
RA   Korch C.T., Spillman M.A., Jackson T.A., Jacobsen B.M., Murphy S.K.,
RA   Lessey B.A., Jordan V.C., Bradford A.P.;
RT   "DNA profiling analysis of endometrial and ovarian cell lines reveals
RT   misidentification, redundancy and contamination.";
RL   Gynecol. Oncol. 127:241-248(2012).
//
RX   PubMed=23415752; DOI=10.1016/j.molonc.2012.12.007;
RA   Stordal B., Timms K., Farrelly A., Gallagher D., Busschots S.,
RA   Renaud M., Thery J., Williams D., Potter J., Tran T., Korpanty G.,
RA   Cremona M., Carey M.S., Li J., Li Y., Aslan O., O'Leary J.J.,
RA   Mills G.B., Hennessy B.T.;
RT   "BRCA1/2 mutation analysis in 41 ovarian cell lines reveals only one
RT   functionally deleterious BRCA1 mutation.";
RL   Mol. Oncol. 7:567-579(2013).
//