Home  |  Contact

Cellosaurus SNU-349 (CVCL_5054)

[Text version]

Cell line name SNU-349
Synonyms SNU349; NCI-SNU-349
Accession CVCL_5054
Resource Identification Initiative To cite this cell line use: SNU-349 (RRID:CVCL_5054)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: Seoul National University (SNU) cell line collection.
Doubling time: 120 hours (PubMed=10619961).
Microsatellite instability: Instable (MSI) (PubMed=10619961; PubMed=31068700).
Omics: Deep exome analysis.
Omics: Deep RNAseq analysis.
Omics: SNP array analysis.
Genome ancestry Source: PubMed=30894373

Origin% genome
African0.29
Native American0.68
East Asian, North61.84
East Asian, South37.03
South Asian0
European, North0.16
European, South0
Disease Clear cell renal cell carcinoma (NCIt: C4033)
Clear cell renal carcinoma (ORDO: Orphanet_319276)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 68Y
Category Cancer cell line
STR profile Source(s): KCLB

Markers:
AmelogeninX,Y
CSF1PO10,12
D3S135814
D5S81810,11,13
D7S82010,11
D13S3179,10
FGA23,24
TH019
TPOX8,11
vWA16,18

Run an STR similarity search on this cell line
Publications

PubMed=10619961; DOI=10.1046/j.1464-410x.2000.00247.x
Shin K.-H., Ku J.-L., Kim W.-H., Lee S.-E., Lee C., Kim S.-W., Park J.-G.
Establishment and characterization of seven human renal cell carcinoma cell lines.
BJU Int. 85:130-138(2000)

PubMed=14634222; DOI=10.1385/1-59259-406-9:111
Park J.-G., Ku J.-L., Park S.-Y.
Isolation and culture of renal cancer cell lines.
Methods Mol. Med. 88:111-119(2004)

PubMed=19956504; DOI=10.4143/crt.2005.37.1.1
Ku J.-L., Park J.-G.
Biology of SNU cell lines.
Cancer Res. Treat. 37:1-19(2005)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=27993170; DOI=10.1186/s12943-016-0565-8
Brodaczewska K.K., Szczylik C., Fiedorowicz M., Porta C., Czarnecka A.M.
Choosing the right cell line for renal cell cancer research.
Mol. Cancer 15:83-83(2016)

PubMed=28489074; DOI=10.1038/ncomms15165
Sinha R., Winer A.G., Chevinsky M., Jakubowski C., Chen Y.-B., Dong Y., Tickoo S.K., Reuter V.E., Russo P., Coleman J.A., Sander C., Hsieh J.J., Hakimi A.A.
Analysis of renal cancer cell lines from two major resources enables genomics-guided cell line selection.
Nat. Commun. 8:15165-15165(2017)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3
Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. III, Barretina J., Gelfand E.T., Bielski C.M., Li H., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

Cross-references
Cell line collections KCLB; 00349
Cell line databases/resources CCLE; SNU349_KIDNEY
Cell_Model_Passport; SIDM01394
DepMap; ACH-000907
Biological sample resources BioSample; SAMN10988037
Chemistry resources PharmacoDB; SNU349_1456_2019
Gene expression databases ArrayExpress; E-MTAB-2770
GEO; GSM888706
Other Wikidata; Q54955177
Polymorphism and mutation databases IARC_TP53; 30164
LiGeA; CCLE_577
Entry history
Entry creation04-Apr-2012
Last entry updated12-Mar-2020
Version number18