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Cellosaurus SNU-410 (CVCL_5059)

[Text version]

Cell line name SNU-410
Synonyms SNU410; NCI-SNU-410
Accession CVCL_5059
Resource Identification Initiative To cite this cell line use: SNU-410 (RRID:CVCL_5059)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: Seoul National University (SNU) cell line collection.
Doubling time: 72 hours (PubMed=12037578).
Omics: Deep exome analysis.
Omics: Deep RNAseq analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Caution: KRAS mutation indicated incorrectly as being p.Gly12Val in PubMed=12037578.
Sequence variations Homozygous for KRAS p.Gly12Asp (c.35G>A) (CCLE).
Homozygous for TP53 p.Ser127Phe (c.380C>T) (CCLE).
Genome ancestry Source: PubMed=30894373

Origin% genome
African0.52
Native American0
East Asian, North66.58
East Asian, South32.02
South Asian0
European, North0
European, South0.89
Disease Pancreatic adenocarcinoma (NCIt: C8294)
Derived from metastatic site: Liver.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 53Y
Category Cancer cell line
STR profile Source(s): KCLB

Markers:
AmelogeninX
CSF1PO12
D3S135815
D5S81812
D7S82012,14
D13S31710,12
FGA23
TH019
TPOX8,12
vWA17

Run an STR similarity search on this cell line
Publications

PubMed=12037578; DOI=10.1007/s00441-001-0510-y
Ku J.-L., Yoon K.-A., Kim W.-H., Jang Y., Suh K.-S., Kim S.-W., Park Y.-H., Park J.-G.
Establishment and characterization of four human pancreatic carcinoma cell lines. Genetic alterations in the TGFBR2 gene but not in the MADH4 gene.
Cell Tissue Res. 308:205-214(2002)

PubMed=19956504; DOI=10.4143/crt.2005.37.1.1
Ku J.-L., Park J.-G.
Biology of SNU cell lines.
Cancer Res. Treat. 37:1-19(2005)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

DOI=10.4172/2324-9293.1000104
Wagenhauser M.U., Ruckert F., Niedergethmann M., Grutzmann R., Saeger H.-D.
Distribution of characteristic mutations in native ductal adenocarcinoma of the pancreas and pancreatic cancer cell lines.
Cell Biol. Res. Ther. 2:1000104.1-1000104.5(2013)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3
Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. III, Barretina J., Gelfand E.T., Bielski C.M., Li H., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

Cross-references
Cell line collections KCLB; 00410
Cell line databases/resources CCLE; SNU410_PANCREAS
Cell_Model_Passport; SIDM01449
DepMap; ACH-000517
Biological sample resources BioSample; SAMN10988085
Gene expression databases ArrayExpress; E-MTAB-2770
GEO; GSM887625
GEO; GSM888710
Other Wikidata; Q54955196
Polymorphism and mutation databases Cosmic; 707183
IARC_TP53; 28388
LiGeA; CCLE_879
Entry history
Entry creation04-Apr-2012
Last entry updated05-Jul-2019
Version number16