ID   SNU-410
AC   CVCL_5059
SY   SNU410; NCI-SNU-410
DR   ArrayExpress; E-MTAB-2770
DR   BioSample; SAMN10988085
DR   CCLE; SNU410_PANCREAS
DR   Cell_Model_Passport; SIDM01449
DR   Cosmic; 707183
DR   DepMap; ACH-000517
DR   GEO; GSM887625
DR   GEO; GSM888710
DR   IARC_TP53; 28388
DR   KCLB; 00410
DR   LiGeA; CCLE_879
DR   PharmacoDB; SNU410_1460_2019
DR   Wikidata; Q54955196
RX   DOI=10.4172/2324-9293.1000104;
RX   PubMed=12037578;
RX   PubMed=19956504;
RX   PubMed=22460905;
RX   PubMed=30894373;
RX   PubMed=31068700;
CC   Part of: Cancer Cell Line Encyclopedia (CCLE) project.
CC   Part of: Seoul National University (SNU) cell line collection.
CC   Doubling time: 72 hours (PubMed=12037578).
CC   Sequence variation: Homozygous for KRAS p.Gly12Asp (c.35G>A) (CCLE).
CC   Sequence variation: Homozygous for TP53 p.Ser127Phe (c.380C>T) (CCLE).
CC   Omics: Deep exome analysis.
CC   Omics: Deep RNAseq analysis.
CC   Omics: SNP array analysis.
CC   Omics: Transcriptome analysis.
CC   Genome ancestry: African=0.52%; Native American=0%; East Asian, North=66.58%; East Asian, South=32.02%; South Asian=0%; European, North=0%; European, South=0.89% (PubMed=30894373).
CC   Caution: KRAS mutation indicated incorrectly as being p.Gly12Val in PubMed=12037578.
CC   Derived from metastatic site: Liver.
ST   Source(s): KCLB
ST   Amelogenin: X
ST   CSF1PO: 12
ST   D13S317: 10,12
ST   D3S1358: 15
ST   D5S818: 12
ST   D7S820: 12,14
ST   FGA: 23
ST   TH01: 9
ST   TPOX: 8,12
ST   vWA: 17
DI   NCIt; C8294; Pancreatic adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens
SX   Male
AG   53Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 06-09-19; Version: 17
//
RX   DOI=10.4172/2324-9293.1000104;
RA   Wagenhauser M.U., Ruckert F., Niedergethmann M., Grutzmann R.,
RA   Saeger H.-D.;
RT   "Distribution of characteristic mutations in native ductal
RT   adenocarcinoma of the pancreas and pancreatic cancer cell lines.";
RL   Cell Biol. Res. Ther. 2:1000104.1-1000104.5(2013).
//
RX   PubMed=12037578; DOI=10.1007/s00441-001-0510-y;
RA   Ku J.-L., Yoon K.-A., Kim W.-H., Jang Y., Suh K.-S., Kim S.-W.,
RA   Park Y.-H., Park J.-G.;
RT   "Establishment and characterization of four human pancreatic carcinoma
RT   cell lines. Genetic alterations in the TGFBR2 gene but not in the
RT   MADH4 gene.";
RL   Cell Tissue Res. 308:205-214(2002).
//
RX   PubMed=19956504; DOI=10.4143/crt.2005.37.1.1;
RA   Ku J.-L., Park J.-G.;
RT   "Biology of SNU cell lines.";
RL   Cancer Res. Treat. 37:1-19(2005).
//
RX   PubMed=22460905; DOI=10.1038/nature11003;
RA   Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A.,
RA   Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A.,
RA   Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J.,
RA   Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E.,
RA   Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J.,
RA   Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C.,
RA   Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C.,
RA   Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N., Mesirov J.P.,
RA   Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L.,
RA   Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R.,
RA   Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.;
RT   "The Cancer Cell Line Encyclopedia enables predictive modelling of
RT   anticancer drug sensitivity.";
RL   Nature 483:603-607(2012).
//
RX   PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747;
RA   Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.;
RT   "An interactive resource to probe genetic diversity and estimated
RT   ancestry in cancer cell lines.";
RL   Cancer Res. 79:1263-1273(2019).
//
RX   PubMed=31068700; DOI=10.1038/s41586-019-1186-3;
RA   Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C.,
RA   McDonald E.R. III, Barretina J., Gelfand E.T., Bielski C.M., Li H.,
RA   Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F.,
RA   Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R.,
RA   Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C.,
RA   Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A.,
RA   Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D.,
RA   Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L.,
RA   Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A.,
RA   Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D.,
RA   Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M.,
RA   Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R.,
RA   Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A.,
RA   Sellers W.R.;
RT   "Next-generation characterization of the Cancer Cell Line
RT   Encyclopedia.";
RL   Nature 569:503-508(2019).
//