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Cellosaurus SNU-466 (CVCL_5064)

[Text version]

Cell line name SNU-466
Synonyms SNU466; NCI-SNU-466
Accession CVCL_5064
Resource Identification Initiative To cite this cell line use: SNU-466 (RRID:CVCL_5064)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: Seoul National University (SNU) cell line collection.
Doubling time: 54 hours (PubMed=11776963).
Omics: Deep exome analysis.
Omics: Deep RNAseq analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Sequence variations Homozygous for PTEN p.Arg159Ser (c.477G>T) (CCLE).
Genome ancestry Source: PubMed=30894373

Origin% genome
African0.92
Native American0
East Asian, North61.85
East Asian, South36.86
South Asian0
European, North0
European, South0.36
Disease Glioblastoma (NCIt: C3058)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 61Y
Category Cancer cell line
STR profile Source(s): KCLB

Markers:
AmelogeninX,Y
CSF1PO12
D3S135815,18
D5S8187,12
D7S82010,12
D13S3178,12
FGA22,24
TH016,9
TPOX9,11
vWA17,18

Run an STR similarity search on this cell line
Publications

PubMed=11776963; DOI=10.1290/1071-2690(2001)037<0625:EACONH>2.0.CO;2
Shin K.-H., Choe G., Park Y.-J., Jang J.-H., Jung H.-W., Park J.-G.
Establishment and characterization of nine human brain tumor cell lines.
In Vitro Cell. Dev. Biol. Anim. 37:625-628(2001)

PubMed=19956504; DOI=10.4143/crt.2005.37.1.1
Ku J.-L., Park J.-G.
Biology of SNU cell lines.
Cancer Res. Treat. 37:1-19(2005)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3
Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. III, Barretina J., Gelfand E.T., Bielski C.M., Li H., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

Cross-references
Cell line collections KCLB; 00466
Cell line databases/resources CCLE; SNU466_CENTRAL_NERVOUS_SYSTEM
Cell_Model_Passport; SIDM01447
DepMap; ACH-000289
Biological sample resources BioSample; SAMN10988076
Chemistry resources PharmacoDB; SNU466_1464_2019
Gene expression databases ArrayExpress; E-MTAB-2770
GEO; GSM887628
GEO; GSM888713
Other Wikidata; Q54955203
Polymorphism and mutation databases IARC_TP53; 30166
LiGeA; CCLE_270
Entry history
Entry creation04-Apr-2012
Last entry updated06-Sep-2019
Version number15