Cellosaurus SNU-478 (CVCL_5065)

Cell line name SNU-478
Synonyms SNU478; NCI-SNU-478
Accession CVCL_5065
Resource Identification Initiative To cite this cell line use: SNU-478 (RRID:CVCL_5065)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: Seoul National University (SNU) cell line collection.
Doubling time: 52 hours (PubMed=12107841).
Microsatellite instability: Stable (MSS) (PubMed=12107841).
Sequence variation: TP53 p.Gly266fs*4 (PubMed=12107841).
Omics: Deep proteome analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Disease Ampulla of Vater adenocarcinoma (NCIt: C6650)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Category Cancer cell line
STR profile Source(s): KCLB

Markers:
AmelogeninX
CSF1PO10,12
D13S3179,11
D3S135816,17
D5S8189,12
D7S8208,11
FGA24
TH017
TPOX10,11
vWA15,16
Publications

PubMed=12107841; DOI=10.1038/sj.bjc.6600440
Ku J.-L., Yoon K.-A., Kim I.-J., Kim W.-H., Jang J.-Y., Suh K.-S., Kim S.-W., Park Y.-H., Hwang J.-H., Yoon Y.-B., Park J.-G.
Establishment and characterisation of six human biliary tract cancer cell lines.
Br. J. Cancer 87:187-193(2002)

PubMed=19956504; DOI=10.4143/crt.2005.37.1.1
Ku J.-L., Park J.-G.
Biology of SNU cell lines.
Cancer Res. Treat. 37:1-19(2005)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

CLPUB00275
Zach S., Birgin E., Ruckert F.
Primary cholangiocellular carcinoma cell lines.
J. Stem Cell Res. Transplant. 2:1013-1013(2015)

PubMed=26951071; DOI=10.1186/s12885-016-2193-5
Lai Z.W., Bolm L., Fuellgraf H., Biniossek M.L., Makowiec F., Hopt U.T., Werner M., Keck T., Bausch D., Sorio C., Scarpa A., Schilling O., Bronsert P., Wellner U.F.
Characterization of various cell lines from different ampullary cancer subtypes and cancer associated fibroblast-mediated responses.
BMC Cancer 16:195-195(2016)

Cross-references
Cell line collections KCLB; 00478
Cell line databases/resources CCLE; SNU478_BILIARY_TRACT
Gene expression databases GEO; GSM887631
GEO; GSM888716
Polymorphism and mutation databases Cosmic; 738871
Proteomic databases PRIDE; PXD002657