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Cellosaurus SNU-489 (CVCL_5069)

[Text version]

Cell line name SNU-489
Synonyms SNU489; NCI-SNU-489
Accession CVCL_5069
Resource Identification Initiative To cite this cell line use: SNU-489 (RRID:CVCL_5069)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: Seoul National University (SNU) cell line collection.
Part of: TCGA-110-CL cell line panel.
Doubling time: 48 hours (PubMed=11776963).
Omics: Deep exome analysis.
Omics: Deep RNAseq analysis.
Omics: SNP array analysis.
Sequence variations Homozygous for TP53 c.994-1G>C; splice acceptor mutation (CCLE).
Genome ancestry Source: PubMed=30894373

Origin% genome
African0.11
Native American0.3
East Asian, North61.65
East Asian, South37.93
South Asian0
European, North0
European, South0
Disease Glioblastoma (NCIt: C3058)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 54Y
Category Cancer cell line
STR profile Source(s): KCLB

Markers:
AmelogeninX,Y
CSF1PO10,11
D3S135815,17
D5S81810,13
D7S8207,11
D13S31710,11
FGA21,23
TH019
TPOX10,11
vWA17

Run an STR similarity search on this cell line
Publications

PubMed=11776963; DOI=10.1290/1071-2690(2001)037<0625:EACONH>2.0.CO;2
Shin K.-H., Choe G., Park Y.-J., Jang J.-H., Jung H.-W., Park J.-G.
Establishment and characterization of nine human brain tumor cell lines.
In Vitro Cell. Dev. Biol. Anim. 37:625-628(2001)

PubMed=19956504; DOI=10.4143/crt.2005.37.1.1
Ku J.-L., Park J.-G.
Biology of SNU cell lines.
Cancer Res. Treat. 37:1-19(2005)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3
Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. III, Barretina J., Gelfand E.T., Bielski C.M., Li H., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

PubMed=31395879; DOI=10.1038/s41467-019-11415-2
Yu K., Chen B., Aran D., Charalel J., Yau C., Wolf D.M., van 't Veer L.J., Butte A.J., Goldstein T., Sirota M.
Comprehensive transcriptomic analysis of cell lines as models of primary tumors across 22 tumor types.
Nat. Commun. 10:3574-3574(2019)

Cross-references
Cell line collections KCLB; 00489
Cell line databases/resources CCLE; SNU489_CENTRAL_NERVOUS_SYSTEM
Cell_Model_Passport; SIDM01446
DepMap; ACH-000543
Biological sample resources BioSample; SAMN10988061
Chemistry resources PharmacoDB; SNU489_1468_2019
Gene expression databases ArrayExpress; E-MTAB-2770
GEO; GSM888717
Other Wikidata; Q54955213
Polymorphism and mutation databases IARC_TP53; 28254
LiGeA; CCLE_278
Entry history
Entry creation04-Apr-2012
Last entry updated19-Dec-2019
Version number16