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Cellosaurus SNU-520 (CVCL_5072)

[Text version]

Cell line name SNU-520
Synonyms SNU520; NCI-SNU-520
Accession CVCL_5072
Resource Identification Initiative To cite this cell line use: SNU-520 (RRID:CVCL_5072)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: Seoul National University (SNU) cell line collection.
Microsatellite instability: Instable (MSI) (PubMed=31068700).
Omics: Deep exome analysis.
Omics: Deep RNAseq analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Sequence variations Has no TP53 mutation (PubMed=9033653).
HLA typing Source: PubMed=25960936
Class I
HLA-AA*24:02,30:01
HLA-BB*53,50
HLA-CC*05:01,06:02
Class II
HLA-DQDQB1*06:13,06:13
Genome ancestry Source: PubMed=30894373

Origin% genome
African0
Native American0
East Asian, North57.76
East Asian, South42.23
South Asian0
European, North0
European, South0
Disease Gastric adenocarcinoma (NCIt: C4004)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 60Y
Category Cancer cell line
STR profile Source(s): KCLB

Markers:
AmelogeninX
CSF1PO10,11
D3S135814,15
D5S81810,13
D7S8209,11
D13S3178
FGA21
TH018,9
TPOX7,8
vWA17,18

Run an STR similarity search on this cell line
Publications

PubMed=9033653; DOI=10.1002/(SICI)1097-0215(19970207)70:4<443::AID-IJC12>3.0.CO;2-G
Park J.-G., Yang H.-K., Kim W.-H., Chung J.-K., Kang M.-S., Lee J.-H., Oh J.-H., Park H.-S., Yeo K.-S., Kang S.H., Song S.-Y., Kang Y.K., Bang Y.-J., Kim Y.I., Kim J.-P.
Establishment and characterization of human gastric carcinoma cell lines.
Int. J. Cancer 70:443-449(1997)

PubMed=19956504; DOI=10.4143/crt.2005.37.1.1
Ku J.-L., Park J.-G.
Biology of SNU cell lines.
Cancer Res. Treat. 37:1-19(2005)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=25960936; DOI=10.4161/21624011.2014.954893
Boegel S., Lower M., Bukur T., Sahin U., Castle J.C.
A catalog of HLA type, HLA expression, and neo-epitope candidates in human cancer cell lines.
OncoImmunology 3:E954893-E954893(2014)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3
Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. III, Barretina J., Gelfand E.T., Bielski C.M., Li H., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

Cross-references
Cell line collections KCLB; 00520
Cell line databases/resources CCLE; SNU520_STOMACH
DepMap; ACH-000908
Biological sample resources BioSample; SAMN10987747
Chemistry resources PharmacoDB; SNU520_1471_2019
Gene expression databases ArrayExpress; E-MTAB-2770
GEO; GSM887633
GEO; GSM888719
Other Wikidata; Q54955217
Polymorphism and mutation databases Cosmic; 685591
Cosmic; 2373752
IARC_TP53; 30167
LiGeA; CCLE_828
Entry history
Entry creation04-Apr-2012
Last entry updated06-Sep-2019
Version number17