ID   SNU-719
AC   CVCL_5086
SY   SNU719; NCI-SNU-719
DR   EFO; EFO_0006760
DR   ArrayExpress; E-MTAB-2706
DR   ArrayExpress; E-MTAB-2770
DR   BioSample; SAMN03473188
DR   BioSample; SAMN10988060
DR   CCLE; SNU719_STOMACH
DR   Cell_Model_Passport; SIDM01450
DR   CGH-DB; 129-1
DR   CGH-DB; 9017-4
DR   Cosmic; 685594
DR   Cosmic; 848144
DR   Cosmic; 869512
DR   Cosmic; 921603
DR   Cosmic; 1090458
DR   Cosmic; 1294959
DR   Cosmic; 1528880
DR   Cosmic; 2646594
DR   Cosmic; 2807652
DR   DepMap; ACH-000898
DR   GEO; GSM552375
DR   GEO; GSM888727
DR   IARC_TP53; 30169
DR   KCLB; 00719
DR   LiGeA; CCLE_869
DR   PharmacoDB; SNU719_1479_2019
DR   Progenetix; CVCL_5086
DR   Wikidata; Q54955255
RX   PubMed=9033653;
RX   PubMed=10812166;
RX   PubMed=15016554;
RX   PubMed=15723654;
RX   PubMed=19956504;
RX   PubMed=22460905;
RX   PubMed=24807215;
RX   PubMed=25485619;
RX   PubMed=25960936;
RX   PubMed=26889033;
RX   PubMed=30894373;
RX   PubMed=31068700;
RX   PubMed=31978347;
CC   Part of: Cancer Cell Line Encyclopedia (CCLE) project.
CC   Part of: Seoul National University (SNU) cell line collection.
CC   Population: Korean.
CC   Characteristics: Contains a complete EBV genome sequenced in PubMed=26889033.
CC   HLA typing: A*24:02,24:02; B*52:01,07:02; C*07:02,12:02; DQB1*05:01,05:01; DRB1*15:02,01:01 (PubMed=25960936).
CC   Sequence variation: Mutation; HGNC; 2514; CTNNB1; Simple; p.Gly34Val (c.101G>T); ClinVar=VCV000017582; Zygosity=Heterozygous (CCLE).
CC   Sequence variation: Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Homozygous (CCLE).
CC   Sequence variation: Mutation; HGNC; 8975; PIK3CA; Simple; p.Pro104Arg (c.311C>G); Zygosity=Heterozygous (CCLE).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; None_reported; -; Zygosity=- (PubMed=9033653).
CC   Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
CC   Omics: Deep exome analysis.
CC   Omics: Deep quantitative proteome analysis.
CC   Omics: Deep RNAseq analysis.
CC   Omics: SNP array analysis.
CC   Omics: Transcriptome analysis.
CC   Genome ancestry: African=0%; Native American=1.31%; East Asian, North=60.01%; East Asian, South=38.67%; South Asian=0%; European, North=0%; European, South=0% (PubMed=30894373).
CC   Derived from sampling site: Stomach.
ST   Source(s): KCLB; PubMed=25877200
ST   Amelogenin: X,Y
ST   CSF1PO: 12
ST   D13S317: 10,11
ST   D16S539: 9,10
ST   D18S51: 13,15
ST   D21S11: 29,30
ST   D3S1358: 15
ST   D5S818: 11,12
ST   D7S820: 10,11
ST   D8S1179: 12
ST   FGA: 21,23
ST   Penta D: 10,11
ST   Penta E: 11,16
ST   TH01: 7,9
ST   TPOX: 8,9
ST   vWA: 16,18
DI   NCIt; C5473; Gastric tubular adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens
SX   Male
AG   53Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 20-05-21; Version: 26
//
RX   PubMed=9033653; DOI=10.1002/(SICI)1097-0215(19970207)70:4<443::AID-IJC12>3.0.CO;2-G;
RA   Park J.-G., Yang H.-K., Kim W.-H., Chung J.-K., Kang M.-S., Lee J.-H.,
RA   Oh J.-H., Park H.-S., Yeo K.-S., Kang S.H., Song S.-Y., Kang Y.K.,
RA   Bang Y.-J., Kim Y.I., Kim J.-P.;
RT   "Establishment and characterization of human gastric carcinoma cell
RT   lines.";
RL   Int. J. Cancer 70:443-449(1997).
//
RX   PubMed=10812166; DOI=10.1016/S0165-4608(99)00217-4;
RA   Chun Y.-H., Kil J.-I., Suh Y.-S., Kim S.-H., Kim H., Park S.-H.;
RT   "Characterization of chromosomal aberrations in human gastric
RT   carcinoma cell lines using chromosome painting.";
RL   Cancer Genet. Cytogenet. 119:18-25(2000).
//
RX   PubMed=15016554; DOI=10.1016/j.virol.2003.12.005;
RA   Oh S.T., Seo J.S., Moon U.Y., Kang K.H., Shin D.-J., Yoon S.K.,
RA   Kim W.-H., Park J.-G., Lee S.K.;
RT   "A naturally derived gastric cancer cell line shows latency I
RT   Epstein-Barr virus infection closely resembling EBV-associated gastric
RT   cancer.";
RL   Virology 320:330-336(2004).
//
RX   PubMed=15723654; DOI=10.1111/j.1349-7006.2005.00016.x;
RA   Takada H., Imoto I., Tsuda H., Sonoda I., Ichikura T., Mochizuki H.,
RA   Okanoue T., Inazawa J.;
RT   "Screening of DNA copy-number aberrations in gastric cancer cell lines
RT   by array-based comparative genomic hybridization.";
RL   Cancer Sci. 96:100-110(2005).
//
RX   PubMed=19956504; DOI=10.4143/crt.2005.37.1.1;
RA   Ku J.-L., Park J.-G.;
RT   "Biology of SNU cell lines.";
RL   Cancer Res. Treat. 37:1-19(2005).
//
RX   PubMed=22460905; DOI=10.1038/nature11003;
RA   Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A.,
RA   Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A.,
RA   Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J.,
RA   Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E.,
RA   Raman P., Shipway A., Engels I.H., Cheng J., Yu G.-Y.K., Yu J.-J.,
RA   Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C.,
RA   Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C.,
RA   Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N.-X., Mesirov J.P.,
RA   Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L.,
RA   Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R.,
RA   Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.;
RT   "The Cancer Cell Line Encyclopedia enables predictive modelling of
RT   anticancer drug sensitivity.";
RL   Nature 483:603-607(2012).
//
RX   PubMed=24807215; DOI=10.1038/ncomms4830;
RA   Liu J., McCleland M., Stawiski E.W., Gnad F., Mayba O., Haverty P.M.,
RA   Durinck S., Chen Y.-J., Klijn C., Jhunjhunwala S., Lawrence M., Liu H.,
RA   Wan Y., Chopra V., Yaylaoglu M.B., Yuan W., Ha C., Gilbert H.N.,
RA   Reeder J., Pau G., Stinson J., Stern H.M., Manning G., Wu T.D.,
RA   Neve R.M., de Sauvage F.J., Modrusan Z., Seshagiri S., Firestein R.,
RA   Zhang Z.;
RT   "Integrated exome and transcriptome sequencing reveals ZAK isoform
RT   usage in gastric cancer.";
RL   Nat. Commun. 5:3830-3830(2014).
//
RX   PubMed=25485619; DOI=10.1038/nbt.3080;
RA   Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z.-S.,
RA   Liu H.-B., Degenhardt J., Mayba O., Gnad F., Liu J.-F., Pau G.,
RA   Reeder J., Cao Y., Mukhyala K., Selvaraj S.K., Yu M.-M., Zynda G.J.,
RA   Brauer M.J., Wu T.D., Gentleman R.C., Manning G., Yauch R.L.,
RA   Bourgon R., Stokoe D., Modrusan Z., Neve R.M., de Sauvage F.J.,
RA   Settleman J., Seshagiri S., Zhang Z.-M.;
RT   "A comprehensive transcriptional portrait of human cancer cell
RT   lines.";
RL   Nat. Biotechnol. 33:306-312(2015).
//
RX   PubMed=25960936; DOI=10.4161/21624011.2014.954893;
RA   Boegel S., Lower M., Bukur T., Sahin U., Castle J.C.;
RT   "A catalog of HLA type, HLA expression, and neo-epitope candidates in
RT   human cancer cell lines.";
RL   OncoImmunology 3:e954893.1-e954893.12(2014).
//
RX   PubMed=26889033; DOI=10.1128/JVI.00060-16;
RA   Kanda T., Furuse Y., Oshitani H., Kiyono T.;
RT   "Highly efficient CRISPR/Cas9-mediated cloning and functional
RT   characterization of gastric cancer-derived Epstein-Barr virus
RT   strains.";
RL   J. Virol. 90:4383-4393(2016).
//
RX   PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747;
RA   Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.;
RT   "An interactive resource to probe genetic diversity and estimated
RT   ancestry in cancer cell lines.";
RL   Cancer Res. 79:1263-1273(2019).
//
RX   PubMed=31068700; DOI=10.1038/s41586-019-1186-3;
RA   Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C.,
RA   McDonald E.R. III, Barretina J., Gelfand E.T., Bielski C.M., Li H.,
RA   Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F.,
RA   Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R.,
RA   Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C.,
RA   Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A.,
RA   Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D.,
RA   Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L.,
RA   Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A.,
RA   Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D.,
RA   Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M.,
RA   Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R.,
RA   Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A.,
RA   Sellers W.R.;
RT   "Next-generation characterization of the Cancer Cell Line
RT   Encyclopedia.";
RL   Nature 569:503-508(2019).
//
RX   PubMed=31978347; DOI=10.1016/j.cell.2019.12.023;
RA   Nusinow D.P., Szpyt J., Ghandi M., Rose C.M., McDonald E.R. III,
RA   Kalocsay M., Jane-Valbuena J., Gelfand E., Schweppe D.K.,
RA   Jedrychowski M., Golji J., Porter D.A., Rejtar T., Wang Y.K.,
RA   Kryukov G.V., Stegmeier F., Erickson B.K., Garraway L.A.,
RA   Sellers W.R., Gygi S.P.;
RT   "Quantitative proteomics of the Cancer Cell Line Encyclopedia.";
RL   Cell 180:387-402.e16(2020).
//