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Cellosaurus SNU-8 (CVCL_5096)

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Cell line name SNU-8
Synonyms SNU8
Accession CVCL_5096
Resource Identification Initiative To cite this cell line use: SNU-8 (RRID:CVCL_5096)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: Seoul National University (SNU) cell line collection.
Doubling time: 44 hours (PubMed=9299249).
Omics: Deep exome analysis.
Omics: Deep RNAseq analysis.
Sequence variations Heterozygous for KRAS p.Gly12Asp (c.35G>A) (CCLE).
Homozygous for TP53 p.Pro142fs (c.425_426delCT) (CCLE).
Genome ancestry Source: PubMed=30894373

Origin% genome
African0.06
Native American0.79
East Asian, North58.48
East Asian, South40.21
South Asian0
European, North0.01
European, South0.45
Disease Ovarian serous cystadenocarcinoma (NCIt: C7978)
Derived from metastatic site: Ascites.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 55Y
Category Cancer cell line
STR profile Source(s): KCLB

Markers:
AmelogeninX
CSF1PO9,12
D3S135814,16
D5S81811,12
D7S8208,12
D13S3178,9
FGA20,26
TH017,9
TPOX11
vWA17

Run an STR similarity search on this cell line
Publications

PubMed=9299249; DOI=10.1006/gyno.1997.4785
Yuan Y., Kim W.-H., Han H.S., Lee J.-H., Park H.-S., Chung J.-K., Kang S.-B., Park J.-G.
Establishment and characterization of human ovarian carcinoma cell lines.
Gynecol. Oncol. 66:378-387(1997)

PubMed=19956504; DOI=10.4143/crt.2005.37.1.1
Ku J.-L., Park J.-G.
Biology of SNU cell lines.
Cancer Res. Treat. 37:1-19(2005)

PubMed=23839242; DOI=10.1038/ncomms3126
Domcke S., Sinha R., Levine D.A., Sander C., Schultz N.
Evaluating cell lines as tumour models by comparison of genomic profiles.
Nat. Commun. 4:2126-2126(2013)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3
Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. III, Barretina J., Gelfand E.T., Bielski C.M., Li H., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

Cross-references
Cell line collections KCLB; 00008
Cell line databases/resources CCLE; SNU8_OVARY
Cell_Model_Passport; SIDM01437
DepMap; ACH-000460
Biological sample resources BioSample; SAMN10988094
Chemistry resources PharmacoDB; SNU8_1482_2019
Gene expression databases ArrayExpress; E-MTAB-2770
Other Wikidata; Q54955270
Polymorphism and mutation databases IARC_TP53; 28385
LiGeA; CCLE_353
Entry history
Entry creation04-Apr-2012
Last entry updated06-Sep-2019
Version number14