ID   SNU-8
AC   CVCL_5096
SY   SNU8
DR   ArrayExpress; E-MTAB-2770
DR   BioSample; SAMN10988094
DR   CCLE; SNU8_OVARY
DR   Cell_Model_Passport; SIDM01437
DR   DepMap; ACH-000460
DR   IARC_TP53; 28385
DR   KCLB; 00008
DR   LiGeA; CCLE_353
DR   PharmacoDB; SNU8_1482_2019
DR   Wikidata; Q54955270
RX   PubMed=9299249;
RX   PubMed=19956504;
RX   PubMed=23839242;
RX   PubMed=30894373;
RX   PubMed=31068700;
CC   Part of: Cancer Cell Line Encyclopedia (CCLE) project.
CC   Part of: Seoul National University (SNU) cell line collection.
CC   Doubling time: 44 hours (PubMed=9299249).
CC   Sequence variation: Heterozygous for KRAS p.Gly12Asp (c.35G>A) (ClinVar=VCV000012582) (CCLE).
CC   Sequence variation: Homozygous for TP53 p.Pro142fs (c.425_426delCT) (CCLE).
CC   Omics: Deep exome analysis.
CC   Omics: Deep RNAseq analysis.
CC   Genome ancestry: African=0.06%; Native American=0.79%; East Asian, North=58.48%; East Asian, South=40.21%; South Asian=0%; European, North=0.01%; European, South=0.45% (PubMed=30894373).
CC   Derived from metastatic site: Ascites.
ST   Source(s): KCLB
ST   Amelogenin: X
ST   CSF1PO: 9,12
ST   D13S317: 8,9
ST   D3S1358: 14,16
ST   D5S818: 11,12
ST   D7S820: 8,12
ST   FGA: 20,26
ST   TH01: 7,9
ST   TPOX: 11
ST   vWA: 17
DI   NCIt; C7978; Ovarian serous cystadenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens
SX   Female
AG   55Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 02-07-20; Version: 15
//
RX   PubMed=9299249; DOI=10.1006/gyno.1997.4785;
RA   Yuan Y., Kim W.-H., Han H.S., Lee J.-H., Park H.-S., Chung J.-K.,
RA   Kang S.-B., Park J.-G.;
RT   "Establishment and characterization of human ovarian carcinoma cell
RT   lines.";
RL   Gynecol. Oncol. 66:378-387(1997).
//
RX   PubMed=19956504; DOI=10.4143/crt.2005.37.1.1;
RA   Ku J.-L., Park J.-G.;
RT   "Biology of SNU cell lines.";
RL   Cancer Res. Treat. 37:1-19(2005).
//
RX   PubMed=23839242; DOI=10.1038/ncomms3126;
RA   Domcke S., Sinha R., Levine D.A., Sander C., Schultz N.;
RT   "Evaluating cell lines as tumour models by comparison of genomic
RT   profiles.";
RL   Nat. Commun. 4:2126-2126(2013).
//
RX   PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747;
RA   Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.;
RT   "An interactive resource to probe genetic diversity and estimated
RT   ancestry in cancer cell lines.";
RL   Cancer Res. 79:1263-1273(2019).
//
RX   PubMed=31068700; DOI=10.1038/s41586-019-1186-3;
RA   Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C.,
RA   McDonald E.R. III, Barretina J., Gelfand E.T., Bielski C.M., Li H.,
RA   Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F.,
RA   Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R.,
RA   Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C.,
RA   Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A.,
RA   Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D.,
RA   Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L.,
RA   Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A.,
RA   Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D.,
RA   Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M.,
RA   Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R.,
RA   Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A.,
RA   Sellers W.R.;
RT   "Next-generation characterization of the Cancer Cell Line
RT   Encyclopedia.";
RL   Nature 569:503-508(2019).
//