ID   SNU-869
AC   CVCL_5101
SY   SNU869
DR   ArrayExpress; E-MTAB-2770
DR   BioSample; SAMN10988091
DR   CCLE; SNU869_BILIARY_TRACT
DR   Cell_Model_Passport; SIDM00159
DR   Cosmic; 738872
DR   Cosmic; 2674054
DR   DepMap; ACH-000182
DR   IARC_TP53; 17161
DR   KCLB; 00869
DR   LiGeA; CCLE_931
DR   PharmacoDB; SNU869_1485_2019
DR   PRIDE; PXD002657
DR   Wikidata; Q54955278
RX   CelloPub=CLPUB00275;
RX   PubMed=12107841;
RX   PubMed=19956504;
RX   PubMed=26951071;
RX   PubMed=27231123;
RX   PubMed=30894373;
RX   PubMed=31068700;
CC   Part of: Cancer Cell Line Encyclopedia (CCLE) project.
CC   Part of: Seoul National University (SNU) cell line collection.
CC   Doubling time: 48 hours (PubMed=12107841).
CC   Sequence variation: Homozygous for KRAS p.Gly12Asp (c.35G>A) (CCLE).
CC   Sequence variation: Heterozygous for PIK3CA p.Glu545Asp (c.1635G>T) (CCLE).
CC   Sequence variation: TP53 p.Asp48Gly (c.143A>G) (PubMed=12107841).
CC   Omics: Deep exome analysis.
CC   Omics: Deep proteome analysis.
CC   Omics: Deep RNAseq analysis.
CC   Genome ancestry: African=15.94%; Native American=0%; East Asian, North=64.53%; East Asian, South=0%; South Asian=0%; European, North=0%; European, South=19.53% (PubMed=30894373).
ST   Source(s): KCLB
ST   CSF1PO: 10
ST   D13S317: 12
ST   D3S1358: 15
ST   D5S818: 12
ST   D7S820: 8,11
ST   FGA: 23
ST   TH01: 7,9
ST   TPOX: 8,10
ST   vWA: 15
DI   NCIt; C6650; Ampulla of Vater adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens
SX   Sex unspecified
AG   Age unspecified
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 06-09-19; Version: 19
//
RX   CelloPub=CLPUB00275;
RA   Zach S., Birgin E., Ruckert F.;
RT   "Primary cholangiocellular carcinoma cell lines.";
RL   J. Stem Cell Res. Transplant. 2:1013-1013(2015).
//
RX   PubMed=12107841; DOI=10.1038/sj.bjc.6600440;
RA   Ku J.-L., Yoon K.-A., Kim I.-J., Kim W.-H., Jang J.-Y., Suh K.-S.,
RA   Kim S.-W., Park Y.-H., Hwang J.-H., Yoon Y.-B., Park J.-G.;
RT   "Establishment and characterisation of six human biliary tract cancer
RT   cell lines.";
RL   Br. J. Cancer 87:187-193(2002).
//
RX   PubMed=19956504; DOI=10.4143/crt.2005.37.1.1;
RA   Ku J.-L., Park J.-G.;
RT   "Biology of SNU cell lines.";
RL   Cancer Res. Treat. 37:1-19(2005).
//
RX   PubMed=26951071; DOI=10.1186/s12885-016-2193-5;
RA   Lai Z.W., Bolm L., Fuellgraf H., Biniossek M.L., Makowiec F.,
RA   Hopt U.T., Werner M., Keck T., Bausch D., Sorio C., Scarpa A.,
RA   Schilling O., Bronsert P., Wellner U.F.;
RT   "Characterization of various cell lines from different ampullary
RT   cancer subtypes and cancer associated fibroblast-mediated responses.";
RL   BMC Cancer 16:195-195(2016).
//
RX   PubMed=27231123; DOI=10.1158/2159-8290.CD-15-1442;
RA   Saha S.K., Gordan J.D., Kleinstiver B.P., Vu P., Najem M.S., Yeo J.-C.,
RA   Shi L., Kato Y., Levin R.S., Webber J.T., Damon L.J., Egan R.K.,
RA   Greninger P., McDermott U., Garnett M.J., Jenkins R.L.,
RA   Rieger-Christ K.M., Sullivan T.B., Hezel A.F., Liss A.S., Mizukami Y.,
RA   Goyal L., Ferrone C.R., Zhu A.X., Joung J.K., Shokat K.M., Benes C.H.,
RA   Bardeesy N.;
RT   "Isocitrate dehydrogenase mutations confer dasatinib hypersensitivity
RT   and SRC dependence in intrahepatic cholangiocarcinoma.";
RL   Cancer Discov. 6:727-739(2016).
//
RX   PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747;
RA   Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.;
RT   "An interactive resource to probe genetic diversity and estimated
RT   ancestry in cancer cell lines.";
RL   Cancer Res. 79:1263-1273(2019).
//
RX   PubMed=31068700; DOI=10.1038/s41586-019-1186-3;
RA   Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C.,
RA   McDonald E.R. III, Barretina J., Gelfand E.T., Bielski C.M., Li H.,
RA   Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F.,
RA   Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R.,
RA   Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C.,
RA   Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A.,
RA   Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D.,
RA   Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L.,
RA   Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A.,
RA   Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D.,
RA   Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M.,
RA   Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R.,
RA   Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A.,
RA   Sellers W.R.;
RT   "Next-generation characterization of the Cancer Cell Line
RT   Encyclopedia.";
RL   Nature 569:503-508(2019).
//