ID   SNU-899
AC   CVCL_5105
SY   SNU899; NCI-SNU-899
DR   BTO; BTO:0005925
DR   ArrayExpress; E-MTAB-2770
DR   BioSample; SAMN10988086
DR   cancercelllines; CVCL_5105
DR   Cell_Model_Passport; SIDM00169
DR   Cosmic; 934175
DR   DepMap; ACH-000692
DR   GEO; GSM887642
DR   GEO; GSM888734
DR   IARC_TP53; 30171
DR   KCLB; 00899
DR   LiGeA; CCLE_315
DR   PharmacoDB; SNU899_1488_2019
DR   Progenetix; CVCL_5105
DR   Wikidata; Q54955284
RX   CelloPub=CLPUB00001;
RX   CelloPub=CLPUB00626;
RX   PubMed=10369293;
RX   PubMed=17923759;
RX   PubMed=19956504;
RX   PubMed=22460905;
RX   PubMed=26589293;
RX   PubMed=30894373;
RX   PubMed=31068700;
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Part of: Seoul National University (SNU) cell line collection.
CC   Population: Korean.
CC   Doubling time: 48 hours (PubMed=10369293).
CC   HLA typing: A*02:06,02:06; B*15:01,15:01; C*04:01,04:01 (PubMed=26589293).
CC   Sequence variation: Mutation; HGNC; 5173; HRAS; Simple; p.Gly13Arg (c.37G>C); ClinVar=VCV000035554; Zygosity=Heterozygous (DepMap).
CC   Omics: Deep exome analysis.
CC   Omics: SNP array analysis.
CC   Omics: Transcriptome analysis by microarray.
CC   Omics: Transcriptome analysis by RNAseq.
CC   Genome ancestry: African=0%; Native American=0.85%; East Asian, North=62.64%; East Asian, South=35.88%; South Asian=0%; European, North=0%; European, South=0.63% (PubMed=30894373).
CC   Derived from site: In situ; Larynx; UBERON=UBERON_0001737.
ST   Source(s): KCLB
ST   Amelogenin: X
ST   CSF1PO: 12
ST   D13S317: 8
ST   D3S1358: 17
ST   D5S818: 11
ST   D7S820: 10,13
ST   FGA: 21
ST   TH01: 9,9.3
ST   TPOX: 8,11
ST   vWA: 14,18
DI   NCIt; C4044; Laryngeal squamous cell carcinoma
DI   ORDO; Orphanet_494550; Squamous cell carcinoma of the larynx
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   56Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 05-10-23; Version: 26
//
RX   CelloPub=CLPUB00001;
RA   Kim K.H., Chung P.-S., Park H.M., Rhee C.-S., Park J.-G.;
RT   "Establishment and characterization of cell lines derived from
RT   squamous cell carcinoma of the head and neck.";
RL   Korean J. Head Neck Oncol. 12:181-187(1996).
//
RX   CelloPub=CLPUB00626;
RA   Chon K.-M., Wang S.-G., Lee B.-J., Lee J.-C., Koo H.-J., Kim S.-H.;
RT   "Establishment of cisplatin resistant head and neck cancer cell lines
RT   and cross-resistance of docetaxel.";
RL   Korean J. Otolaryngol. 48:651-655(2005).
//
RX   PubMed=10369293; DOI=10.1097/00005537-199906000-00025;
RA   Ku J.-L., Kim W.-H., Lee J.-H., Park H.-S., Kim K.H., Sung M.-W.,
RA   Park J.-G.;
RT   "Establishment and characterization of human laryngeal squamous cell
RT   carcinoma cell lines.";
RL   Laryngoscope 109:976-982(1999).
//
RX   PubMed=17923759; DOI=10.3346/jkms.2007.22.S.S73;
RA   Lee B.-J., Lee B.-H., Wang S.-G., Lee J.-C., Roh H.-J., Goh E.-K.,
RA   Kim C.-M., Jun E.-S.;
RT   "Change of the expression of human telomerase reverse transcriptase
RT   mRNA and human telomerase RNA after cisplatin and 5-fluorouracil
RT   exposure in head and neck squamous cell carcinoma cell lines.";
RL   J. Korean Med. Sci. 22:S73-S78(2007).
//
RX   PubMed=19956504; DOI=10.4143/crt.2005.37.1.1;
RA   Ku J.-L., Park J.-G.;
RT   "Biology of SNU cell lines.";
RL   Cancer Res. Treat. 37:1-19(2005).
//
RX   PubMed=22460905; DOI=10.1038/nature11003;
RA   Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A.,
RA   Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A.,
RA   Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J.,
RA   Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E.,
RA   Raman P., Shipway A., Engels I.H., Cheng J., Yu G.-Y.K., Yu J.-J.,
RA   Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C.,
RA   Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C.,
RA   Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N.-X., Mesirov J.P.,
RA   Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L.,
RA   Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M.L., Golub T.R.,
RA   Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.;
RT   "The Cancer Cell Line Encyclopedia enables predictive modelling of
RT   anticancer drug sensitivity.";
RL   Nature 483:603-607(2012).
//
RX   PubMed=26589293; DOI=10.1186/s13073-015-0240-5;
RA   Scholtalbers J., Boegel S., Bukur T., Byl M., Goerges S., Sorn P.,
RA   Loewer M., Sahin U., Castle J.C.;
RT   "TCLP: an online cancer cell line catalogue integrating HLA type,
RT   predicted neo-epitopes, virus and gene expression.";
RL   Genome Med. 7:118.1-118.7(2015).
//
RX   PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747;
RA   Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.;
RT   "An interactive resource to probe genetic diversity and estimated
RT   ancestry in cancer cell lines.";
RL   Cancer Res. 79:1263-1273(2019).
//
RX   PubMed=31068700; DOI=10.1038/s41586-019-1186-3;
RA   Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C.,
RA   McDonald E.R. III, Barretina J.G., Gelfand E.T., Bielski C.M., Li H.-X.,
RA   Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F.,
RA   Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R.,
RA   Lu Y.-L., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C.,
RA   Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A.,
RA   Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D.,
RA   Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L.,
RA   Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A.,
RA   Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D.,
RA   Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M.,
RA   Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R.,
RA   Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A.,
RA   Sellers W.R.;
RT   "Next-generation characterization of the Cancer Cell Line
RT   Encyclopedia.";
RL   Nature 569:503-508(2019).
//