Cellosaurus HCC2279 (CVCL_5131)

Cell line name HCC2279
Synonyms HCC-2279
Accession CVCL_5131
Resource Identification Initiative To cite this cell line use: HCC2279 (RRID:CVCL_5131)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: MD Anderson Cell Lines Project.
Omics: Deep RNAseq analysis.
Omics: Protein expression by reverse-phase protein arrays.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Misspelling: HCC227; In EFO EFO_0005374.
Disease Adenosquamous lung carcinoma (NCIt: C9133)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Category Cancer cell line
STR profile Source(s): ATCC; KCLB; PubMed=20679594; PubMed=25877200

Markers:
AmelogeninX
CSF1PO12
D13S31712
D16S53911
D18S5120
D21S1129,32.2
D3S135817,18
D5S81810,11
D7S82011
D8S117916
FGA19,25 (KCLB)
19 (PubMed=25877200)
Penta D10,12
Penta E12,14
TH019
TPOX11
vWA14,17
Web pages http://www.utsouthwestern.edu/edumedia/edufiles/about_us/admin_offices/technology_development/available_technologies/cell-lines.pdf
http://tcpaportal.org/mclp/
Publications

PubMed=10353731
Wistuba I.I., Bryant D., Behrens C., Milchgrub S., Virmani A.K., Ashfaq R., Minna J.D., Gazdar A.F.
Comparison of features of human lung cancer cell lines and their corresponding tumors.
Clin. Cancer Res. 5:991-1000(1999)

PubMed=20679594; DOI=10.1093/jnci/djq279
Gazdar A.F., Girard L., Lockwood W.W., Lam W.L., Minna J.D.
Lung cancer cell lines as tools for biomedical discovery and research.
J. Natl. Cancer Inst. 102:1310-1321(2010)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=25485619; DOI=10.1038/nbt.3080
Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z., Liu H., Degenhardt J., Mayba O., Gnad F., Liu J., Pau G., Reeder J., Cao Y., Mukhyala K., Selvaraj S.K., Yu M., Zynda G.J., Brauer M.J., Wu T.D., Gentleman R.C., Manning G., Yauch R.L., Bourgon R., Stokoe D., Modrusan Z., Neve R.M., de Sauvage F.J., Settleman J., Seshagiri S., Zhang Z.
A comprehensive transcriptional portrait of human cancer cell lines.
Nat. Biotechnol. 33:306-312(2015)

PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005
Li J., Zhao W., Akbani R., Liu W., Ju Z., Ling S., Vellano C.P., Roebuck P., Yu Q., Eterovic A.K., Byers L.A., Davies M.A., Deng W., Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D., Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y., Mills G.B., Liang H.
Characterization of human cancer cell lines by reverse-phase protein arrays.
Cancer Cell 31:225-239(2017)

Cross-references
Cell line collections ATCC; CRL-2870 - Discontinued
KCLB; 72279
Cell line databases/resources CCLE; HCC2279_LUNG
IGRhCellID; HCC2279GEO
Ontologies EFO; EFO_0005374
EFO; EFO_0006431
Biological sample resources BioSample; SAMN03472992
Gene expression databases GEO; GSM63348
GEO; GSM253421
GEO; GSM434283
GEO; GSM794392
GEO; GSM887050
GEO; GSM888120
Polymorphism and mutation databases Cosmic; 903642
Cosmic; 1128248
Cosmic; 1146930