Cellosaurus HCC461 (CVCL_5135)

Cell line name HCC461
Synonyms HCC0461
Accession CVCL_5135
Resource Identification Initiative To cite this cell line use: HCC461 (RRID:CVCL_5135)
Comments Omics: Deep RNAseq analysis.
Omics: Protein expression by reverse-phase protein arrays.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 69Y
Category Cancer cell line
STR profile Source(s): PubMed=20679594; PubMed=25877200

Markers:
AmelogeninX (PubMed=20679594)
X,Y (PubMed=25877200)
CSF1PO10,12
D13S31710,11
D16S53911,12
D18S5112,14
D21S1130
D3S135815,18
D5S81810,13
D7S8209,11
D8S117913,14
FGA21,22
Penta D10,13
Penta E13
TH017,9
TPOX8
vWA16,17
Web pages http://www.utsouthwestern.edu/edumedia/edufiles/about_us/admin_offices/technology_development/available_technologies/cell-lines.pdf
Publications

PubMed=10353731
Wistuba I.I., Bryant D., Behrens C., Milchgrub S., Virmani A.K., Ashfaq R., Minna J.D., Gazdar A.F.
Comparison of features of human lung cancer cell lines and their corresponding tumors.
Clin. Cancer Res. 5:991-1000(1999)

PubMed=20679594; DOI=10.1093/jnci/djq279
Gazdar A.F., Girard L., Lockwood W.W., Lam W.L., Minna J.D.
Lung cancer cell lines as tools for biomedical discovery and research.
J. Natl. Cancer Inst. 102:1310-1321(2010)

PubMed=22961666; DOI=10.1158/2159-8290.CD-12-0112
Byers L.A., Wang J., Nilsson M.B., Fujimoto J., Saintigny P., Yordy J., Giri U., Peyton M., Fan Y.H., Diao L., Masrorpour F., Shen L., Liu W., Duchemann B., Tumula P., Bhardwaj V., Welsh J., Weber S., Glisson B.S., Kalhor N., Wistuba I.I., Girard L., Lippman S.M., Mills G.B., Coombes K.R., Weinstein J.N., Minna J.D., Heymach J.V.
Proteomic profiling identifies dysregulated pathways in small cell lung cancer and novel therapeutic targets including PARP1.
Cancer Discov. 2:798-811(2012)

PubMed=25485619; DOI=10.1038/nbt.3080
Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z., Liu H., Degenhardt J., Mayba O., Gnad F., Liu J., Pau G., Reeder J., Cao Y., Mukhyala K., Selvaraj S.K., Yu M., Zynda G.J., Brauer M.J., Wu T.D., Gentleman R.C., Manning G., Yauch R.L., Bourgon R., Stokoe D., Modrusan Z., Neve R.M., de Sauvage F.J., Settleman J., Seshagiri S., Zhang Z.
A comprehensive transcriptional portrait of human cancer cell lines.
Nat. Biotechnol. 33:306-312(2015)

Cross-references
Cell line databases/resources IGRhCellID; HCC461GEO
Ontologies EFO; EFO_0003134
Biological sample resources BioSample; SAMN03471006
Gene expression databases ArrayExpress; E-MTAB-2706
GEO; GSM62336
GEO; GSM253392
GEO; GSM434262
GEO; GSM794380
Polymorphism and mutation databases Cosmic; 903632
Cosmic; 1146938