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Cellosaurus HCE-7 (CVCL_5138)

[Text version]

Cell line name HCE-7
Synonyms HCE7; HCE-7 (NM); HCE-7(NM)
Accession CVCL_5138
Resource Identification Initiative To cite this cell line use: HCE-7 (RRID:CVCL_5138)
Comments Characteristics: Established from a tumor transplanted in nude mice.
Doubling time: 53 hours (PubMed=2415247).
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Derived from sampling site: Esophagus.
Disease Esophageal squamous cell carcinoma (NCIt: C4024)
Squamous cell carcinoma of the esophagus (ORDO: Orphanet_99977)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_1271 ! HCE-4
Sex of cell Female
Age at sampling 50Y
Category Cancer cell line

Banks-Schlegel S.P., Quintero J.
Growth and differentiation of human esophageal carcinoma cell lines.
Cancer Res. 46:250-258(1986)

PubMed=2420787; DOI=10.1016/S0021-9258(17)38506-X
Banks-Schlegel S.P., Quintero J.
Human esophageal carcinoma cells have fewer, but higher affinity epidermal growth factor receptors.
J. Biol. Chem. 261:4359-4362(1986)

PubMed=2302677; DOI=10.1016/0165-4608(90)90073-j
Whang-Peng J., Banks-Schlegel S.P., Lee E.C.
Cytogenetic studies of esophageal carcinoma cell lines.
Cancer Genet. Cytogenet. 45:101-120(1990)

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458
Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

Cell line databases/resources Cell_Model_Passport; SIDM00067
Anatomy/cell type resources BTO; BTO:0002818
Chemistry resources PharmacoDB; HCE7_515_2019
Encyclopedic resources Wikidata; Q54881852
Gene expression databases ArrayExpress; E-MTAB-3610
GEO; GSM827169
GEO; GSM1669866
Polymorphism and mutation databases Cosmic; 923187
Cosmic; 932975
Cosmic; 2668298
Progenetix; CVCL_5138
Entry history
Entry creation04-Apr-2012
Last entry update23-Sep-2021
Version number14