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Cellosaurus PMC42 (CVCL_5215)

[Text version]

Cell line name PMC42
Synonyms PMC-42; PMC42-ET; PMC-42 ET; PMC42ET
Accession CVCL_5215
Resource Identification Initiative To cite this cell line use: PMC42 (RRID:CVCL_5215)
Comments Part of: GrayJW Breast Cancer Cell Line Panel.
Omics: Deep exome analysis.
Omics: SNP array analysis.
Disease Breast carcinoma (NCIt: C4872)
Derived from metastatic site: Pleural effusion.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_5216 (PMC42-LA)
Sex of cell Female
Age at sampling 68Y
Category Cancer cell line
STR profile Source(s): PubMed=28889351

Markers:
AmelogeninX
CSF1PO10,12
D5S81811,12
D7S8207,9
D13S31714
D16S5399,11
D21S1130,31.2
TH016
TPOX8,11
vWA15,19

Run an STR similarity search on this cell line
Web pages http://www.pawefish.path.cam.ac.uk/BreastCellLineDescriptions/pmc42.htm
https://www.synapse.org/#!Synapse:syn2346643/wiki/62255
Publications

PubMed=6572752; DOI=10.1093/jnci/70.4.649
Whitehead R.H., Bertoncello I., Webber L.M., Pedersen J.S.
A new human breast carcinoma cell line (PMC42) with stem cell characteristics. I. Morphologic characterization.
J. Natl. Cancer Inst. 70:649-661(1983)

PubMed=6606728; DOI=10.1093/jnci/71.6.1193
Whitehead R.H., Monaghan P., Webber L.M., Bertoncello I., Vitali A.A.
A new human breast carcinoma cell line (PMC42) with stem cell characteristics. II. Characterization of cells growing as organoids.
J. Natl. Cancer Inst. 71:1193-1203(1983)

PubMed=6381852; DOI=10.1093/jnci/73.3.643
Whitehead R.H., Quirk S.J., Vitali A.A., Funder J.W., Sutherland R.L., Murphy L.C.
A new human breast carcinoma cell line (PMC42) with stem cell characteristics. III. Hormone receptor status and responsiveness.
J. Natl. Cancer Inst. 73:643-648(1984)

PubMed=2228321; DOI=10.1002/ijc.2910460531
Monaghan P., Ormerod M.G., O'Hare M.J.
Epidermal growth factor receptors and EGF-responsiveness of the human breast-carcinoma cell line PMC42.
Int. J. Cancer 46:935-943(1990)

DOI=10.1016/B978-0-12-333530-2.50009-5
Leibovitz A.
Cell lines from human breast.
(In) Atlas of human tumor cell lines; Hay R.J., Park J.-G., Gazdar A.F. (eds.); pp.161-184; Academic Press; New York (1994)

PubMed=11044355; DOI=10.1054/bjoc.2000.1458
Davidson J.M., Gorringe K.L., Chin S.-F., Orsetti B., Besret C., Courtay-Cahen C., Roberts I., Theillet C., Caldas C., Edwards P.A.W.
Molecular cytogenetic analysis of breast cancer cell lines.
Br. J. Cancer 83:1309-1317(2000)

PubMed=11161701; DOI=10.1006/excr.2000.5106
Ackland M.L., Michalczyk A., Whitehead R.H.
PMC42, a novel model for the differentiated human breast.
Exp. Cell Res. 263:14-22(2001)

CLPUB00423
Morrison B.J.
Breast cancer stem cells: tumourspheres and implications for therapy.
Thesis PhD (2010), Griffith University, Australia

PubMed=24176112; DOI=10.1186/gb-2013-14-10-r110
Daemen A., Griffith O.L., Heiser L.M., Wang N.J., Enache O.M., Sanborn Z., Pepin F., Durinck S., Korkola J.E., Griffith M., Hur J.S., Huh N., Chung J., Cope L., Fackler M.J., Umbricht C., Sukumar S., Seth P., Sukhatme V.P., Jakkula L.R., Lu Y., Mills G.B., Cho R.J., Collisson E.A., van't Veer L.J., Spellman P.T., Gray J.W.
Modeling precision treatment of breast cancer.
Genome Biol. 14:R110.1-R110.14(2013)

PubMed=28889351; DOI=10.1007/s10549-017-4496-x
Saunus J.M., Smart C.E., Kutasovic J.R., Johnston R.L., Kalita-de Croft P., Miranda M., Rozali E.N., Vargas A.C., Reid L.E., Lorsy E., Cocciardi S., Seidens T., McCart Reed A.E., Dalley A.J., Wockner L.F., Johnson J., Sarkar D., Askarian-Amiri M.E., Simpson P.T., Khanna K.K., Chenevix-Trench G., Al-Ejeh F., Lakhani S.R.
Multidimensional phenotyping of breast cancer cell lines to guide preclinical research.
Breast Cancer Res. Treat. 167:289-301(2018)

Cross-references
Chemistry resources PharmacoDB; PMC42_1275_2019
Gene expression databases GEO; GSM217595
GEO; GSM1172988
Other Wikidata; Q54947618
Entry history
Entry creation04-Apr-2012
Last entry updated06-Sep-2019
Version number17