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Cellosaurus LAD 1 (CVCL_5220)

[Text version]
Cell line name LAD 1
Synonyms LAD1; LADR; Laboratory of Allergic Diseases 1
Accession CVCL_5220
Resource Identification Initiative To cite this cell line use: LAD 1 (RRID:CVCL_5220)
Comments Characteristics: KITLG dependent.
Doubling time: ~28 days (DOI=10.1016/j.jaci.2018.12.550).
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Cell type: Mast cell; CL=CL_0000097.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_0387 ! LAD 2
Sex of cell Male
Age at sampling 44Y
Category Factor-dependent cell line
Web pages http://www.cells-talk.com/index.php/page/copelibrary?key=LAD1
Publications

PubMed=12801524; DOI=10.1016/S0145-2126(02)00343-0
Kirshenbaum A.S., Akin C., Wu Y.-L., Rottem M., Goff J.P., Beaven M.A., Rao V.K., Metcalfe D.D.
Characterization of novel stem cell factor responsive human mast cell lines LAD 1 and 2 established from a patient with mast cell sarcoma/leukemia; activation following aggregation of FcepsilonRI or FcgammaRI.
Leuk. Res. 27:677-682(2003)

PubMed=25149487; DOI=10.1007/978-1-4939-1173-8_8
Passante E.
Mast cell and basophil cell lines: a compendium.
Methods Mol. Biol. 1192:101-113(2014)

DOI=10.1016/j.jaci.2018.12.550
Kirshenbaum A.S., Yin Y., Sundstrom J.B., Bandara G., Metcalfe D.D.
Characterization and comparison of human LAD1 mast cells with human LAD2 mast cells.
J. Allergy Clin. Immunol. 143 Suppl. 1:AB180-AB180(2019)

PubMed=31698677; DOI=10.3390/ijms20225520
Kirshenbaum A.S., Yin Y.-Z., Sundstrom J.B., Bandara G., Metcalfe D.D.
Description and characterization of a novel human mast cell line for scientific study.
Int. J. Mol. Sci. 20:5520.1-5520.9(2019)

Cross-references
Encyclopedic resources Wikidata; Q54901896
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number14