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Cellosaurus OCI-AML-4 (CVCL_5224)

[Text version]
Cell line name OCI-AML-4
Synonyms OCI/AML-4; OCI-AML4; OCI/AML4; OCI AML4; OCIAML4; Ontario Cancer Institute-Acute Myeloid Leukemia-4
Accession CVCL_5224
Resource Identification Initiative To cite this cell line use: OCI-AML-4 (RRID:CVCL_5224)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Doubling time: ~24-30 hours (DSMZ=ACC-729).
Donor information: Originally the patient was suffering from Hodgkin lymphoma.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Disease Adult acute myeloid leukemia (NCIt: C9154)
Acute myeloid leukemia (ORDO: Orphanet_519)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 35Y
Category Cancer cell line
STR profile Source(s): DepMap; DSMZ

Markers:
AmelogeninX
CSF1PO10,12
D2S133819,24
D3S135814,18
D5S81811,12
D7S82012
D8S117913,15
D13S3178,11
D16S53911
D18S5115,16
D19S43312,14
D21S1131.2,32.2
FGA19,24
Penta D12
Penta E10,14
TH017
TPOX8,9
vWA14,17

Run an STR similarity search on this cell line
Publications

PubMed=1715961
Koistinen P., Wang C., Yang G.S., Wang Y.-F., Williams D.E., Lyman S.D., Minden M.D., McCulloch E.A.
OCI/AML-4 an acute myeloblastic leukemia cell line: regulation and response to cytosine arabinoside.
Leukemia 5:704-711(1991)

PubMed=29533902; DOI=10.1515/hsz-2017-0321
Drexler H.G., Pommerenke C., Eberth S., Nagel S.
Hodgkin lymphoma cell lines: to separate the wheat from the chaff.
Biol. Chem. 399:511-523(2018)

Cross-references
Cell line collections (Providers) DSMZ; ACC-729
Cell line databases/resources cancercelllines; CVCL_5224
DepMap; ACH-001613
DSMZCellDive; ACC-729
Encyclopedic resources Wikidata; Q54931743
Polymorphism and mutation databases Cosmic; 787468
Cosmic; 975290
Cosmic; 1281345
Cosmic; 1319547
Cosmic; 2306233
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number23