Cellosaurus LoVo-92 (CVCL_5237)

Cell line name LoVo-92
Synonyms Lovo-92; Lovo 92; Lovo92
Accession CVCL_5237
Resource Identification Initiative To cite this cell line use: LoVo-92 (RRID:CVCL_5237)
Disease Colon adenocarcinoma (NCIt: C4349)
Derived from metastatic site: Left supraclavicular lymph node.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0399 (LoVo)
Children: CVCL_6A75 (Lovo-143X19); CVCL_6A76 (Lovo-143X3); CVCL_5235 (Lovo-175X2); CVCL_5236 (Lovo-273X17); CVCL_5238 (LoVo-li)
Sex of cell Male
Category Cancer cell line
Publications

PubMed=8632910
Pocard M., Chevillard S., Villaudy J., Poupon M.-F., Dutrillaux B., Remvikos Y.
Different p53 mutations produce distinct effects on the ability of colon carcinoma cells to become blocked at the G1/S boundary after irradiation.
Oncogene 12:875-882(1996)

PubMed=9989828; DOI=10.1038/sj.onc.1202336
Soulie P., Poupon M.-F., Remvikos Y., Dutrillaux B., Muleris M.
Distinct chromosomal alterations associated with TP53 status of LoVo cells under PALA selective pressure: a parallel with cytogenetic pathways of colorectal cancers.
Oncogene 18:775-781(1999)

PubMed=17339891; DOI=10.1038/sj.bjc.6603639
Giovannetti E., Backus H.H.J., Wouters D., Ferreira C.G., van Houten V.M.M., Brakenhoff R.H., Poupon M.-F., Azzarello A., Pinedo H.M., Peters G.J.
Changes in the status of p53 affect drug sensitivity to thymidylate synthase (TS) inhibitors by altering TS levels.
Br. J. Cancer 96:769-775(2007)

PubMed=18600534; DOI=10.1080/15257770802145512
Giovannetti E., Backus H.H.J., Wouters D., Peters G.J.
Functional inactivity and mutations of p53 differentially affect sensitivity to 5-fluorouracil and antifolate inhibitors of thymidylate synthase (TS) by altering TS levels in colorectal cancer cells.
Nucleosides Nucleotides Nucleic Acids 27:740-745(2008)

Cross-references
Ontologies BTO; BTO:0004146
Gene expression databases GEO; GSM503149