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Cellosaurus GFPu-1 (CVCL_5285)

[Text version]
Cell line name GFPu-1
Synonyms GFPu1
Accession CVCL_5285
Resource Identification Initiative To cite this cell line use: GFPu-1 (RRID:CVCL_5285)
Comments Characteristics: Reporter cell line to study protein aggregation and the function of the ubiquitin-proteasome system (UPS).
Characteristics: Expresses GFP tagged at the C-terminus with the degradation signal CL1 (ACKNWFSSLSHFVIHL).
Transfected with: UniProtKB; P42212; GFP (with p.Phe64Leu, p.Ser65Thr and p.His231Leu = EGFP).
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0045 (HEK293)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
STR profile Source(s): ATCC

Markers:
AmelogeninX
CSF1PO12
D5S8188
D7S82011,12
D13S31712,14
D16S5399,13
TH017,9.3
TPOX11
vWA16,19

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Publications

PubMed=11375494; DOI=10.1126/science.292.5521.1552
Bence N.F., Sampat R.M., Kopito R.R.
Impairment of the ubiquitin-proteasome system by protein aggregation.
Science 292:1552-1555(2001)

Cross-references
Cell line collections (Providers) ATCC; CRL-2794
Cell line databases/resources CLO; CLO_0003478
Encyclopedic resources Wikidata; Q54835743
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number13