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Cellosaurus KPMM2 (CVCL_5311)

Cell line name KPMM2
Synonyms KPMM-2
Accession CVCL_5311
Resource Identification Initiative To cite this cell line use: KPMM2 (RRID:CVCL_5311)
Comments Population: Japanese.
Characteristics: Produces IgG lambda.
Characteristics: IL6 dependent.
Doubling time: ~48 hours (Note=With IL6), ~72 hours (Note=Without IL6) (PubMed=7723407).
Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
Disease Plasma cell myeloma (NCIt: C3242)
Multiple myeloma (ORDO: Orphanet_29073)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 77Y
Category Cancer cell line
Web pages https://www.keatslab.org/myeloma-cell-lines/hmcl-characteristics
http://www.cells-talk.com/index.php/page/copelibrary?key=KPMM2
Publications

PubMed=7723407
Goto H., Shimazaki C., Tatsumi T., Yamagata N., Fujita N., Tsuchiya M., Koishihara Y., Ohsugi Y., Nakagawa M.
Establishment of a novel myeloma cell line KPMM2 carrying t(3;14)(q21;q32), which proliferates specifically in response to interleukin-6 through an autocrine mechanism.
Leukemia 9:711-718(1995)

PubMed=8797890; DOI=10.1111/j.1349-7006.1996.tb02108.x
Tatsumi T., Shimazaki C., Goto H., Araki S.-i., Sudo Y., Yamagata N., Ashihara E., Inaba T., Fujita N., Nakagawa M.
Expression of adhesion molecules on myeloma cells.
Jpn. J. Cancer Res. 87:837-842(1996)

DOI=10.1007/0-306-46877-8_4
Jernberg-Wiklund H., Nilsson K.
Multiple myeloma cell lines.
(In) Human cell culture. Vol. 3. Cancer Cell Lines part 3; Masters J.R.W., Palsson B.O. (eds.); pp.81-155; Kluwer Academic Publishers; New York (2000)

PubMed=10936422; DOI=10.1016/S0145-2126(99)00195-2
Drexler H.G., Matsuo Y.
Malignant hematopoietic cell lines: in vitro models for the study of multiple myeloma and plasma cell leukemia.
Leuk. Res. 24:681-703(2000)

DOI=10.1016/B978-0-12-221970-2.50457-5
Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In) ISBN 9780122219702; pp.1-733; Academic Press; London (2001)

Cross-references
Encyclopedic resources Wikidata; Q54900441
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number16