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Cellosaurus OH-2 [Human plasma cell myeloma] (CVCL_5442)

Cell line name OH-2 [Human plasma cell myeloma]
Synonyms OH2
Accession CVCL_5442
Resource Identification Initiative To cite this cell line use: OH-2 [Human plasma cell myeloma] (RRID:CVCL_5442)
Comments Characteristics: Produces IgG kappa.
Characteristics: IL6 dependent.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Disease Plasma cell myeloma (NCIt: C3242)
Multiple myeloma (ORDO: Orphanet_29073)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 52Y
Category Cancer cell line
Web pages https://www.keatslab.org/myeloma-cell-lines/hmcl-characteristics
http://www.cells-talk.com/index.php/page/copelibrary?key=OH-2
Publications

PubMed=8062895; DOI=10.1111/j.1600-0609.1994.tb00176.x
Borset M., Waage A., Brekke O.L., Helseth E.
TNF and IL-6 are potent growth factors for OH-2, a novel human myeloma cell line.
Eur. J. Haematol. 53:31-37(1994)

DOI=10.1007/0-306-46877-8_4
Jernberg-Wiklund H., Nilsson K.
Multiple myeloma cell lines.
(In) Human cell culture. Vol. 3. Cancer Cell Lines part 3; Masters J.R.W., Palsson B.O. (eds.); pp.81-155; Kluwer Academic Publishers; New York (2000)

PubMed=10936422; DOI=10.1016/S0145-2126(99)00195-2
Drexler H.G., Matsuo Y.
Malignant hematopoietic cell lines: in vitro models for the study of multiple myeloma and plasma cell leukemia.
Leuk. Res. 24:681-703(2000)

PubMed=11154231; DOI=10.1182/blood.V97.2.516
Hjertner O., Hjorth-Hansen H., Borset M., Seidel C., Waage A., Sundan A.
Bone morphogenetic protein-4 inhibits proliferation and induces apoptosis of multiple myeloma cells.
Blood 97:516-522(2001)

CLPUB00604
Chow S.
Targeted capture and sequencing of immunoglobulin rearrangements in multiple myeloma to enable detection of minimal residual disease.
Thesis MSc (2017), University of Toronto, Canada

PubMed=32123307; DOI=10.1038/s41375-020-0785-1
Sarin V., Yu K., Ferguson I.D., Gugliemini O., Nix M.A., Hann B., Sirota M., Wiita A.P.
Evaluating the efficacy of multiple myeloma cell lines as models for patient tumors via transcriptomic correlation analysis.
Leukemia 34:2754-2765(2020)

Cross-references
Encyclopedic resources Wikidata; Q54931884
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number17