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Cellosaurus SK-LC-2 (CVCL_5468)

Cell line name SK-LC-2
Synonyms SK LC 02; SK-LC2
Accession CVCL_5468
Resource Identification Initiative To cite this cell line use: SK-LC-2 (RRID:CVCL_5468)
Comments From: Memorial Sloan Kettering Cancer Center; New York; USA.
Miscellaneous: STR profile and age/sex of donor from MSKCC antibody and bioresource core facility.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Pro85fs (c.253delC); Zygosity=Unspecified (PubMed=12794755).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 65Y
Category Cancer cell line
STR profile Source(s): MSKCC

Markers:
AmelogeninX,Y
CSF1PO12
D2S133817,18
D3S135816
D5S81811,12
D7S8209
D8S117913,14
D13S31712
D16S53912
D18S5117
D19S43313,15.2
D21S1129
FGA20
TH019.3
TPOX8
vWA16

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Publications

PubMed=6208122; DOI=10.1089/hyb.1.1982.1.139
Anger B.R., Lloyd K.O., Oettgen H.F., Old L.J.
Mouse monoclonal IgM antibody against human lung cancer line SK-LC-3 with specificity for H(O) blood group antigen.
Hybridoma 1:139-147(1982)

PubMed=6582512; DOI=10.1073/pnas.81.2.568
Mattes M.J., Cordon-Cardo C., Lewis J.L. Jr., Old L.J., Lloyd K.O.
Cell surface antigens of human ovarian and endometrial carcinoma defined by mouse monoclonal antibodies.
Proc. Natl. Acad. Sci. U.S.A. 81:568-572(1984)

PubMed=3518877; DOI=10.3109/07357908609038260
Fogh J.
Human tumor lines for cancer research.
Cancer Invest. 4:157-184(1986)

PubMed=2540905
Takahashi T., Obata Y., Sekido Y., Hida T., Ueda R., Watanabe H., Ariyoshi Y., Sugiura T., Takahashi T.
Expression and amplification of myc gene family in small cell lung cancer and its relation to biological characteristics.
Cancer Res. 49:2683-2688(1989)

PubMed=2784858; DOI=10.1073/pnas.86.8.2804
Knuth A., Wolfel T., Klehmann E., Boon T., Meyer zum Buschenfelde K.-H.
Cytolytic T-cell clones against an autologous human melanoma: specificity study and definition of three antigens by immunoselection.
Proc. Natl. Acad. Sci. U.S.A. 86:2804-2808(1989)

PubMed=9636188; DOI=10.1073/pnas.95.13.7556
Kaplan D.H., Shankaran V., Dighe A.S., Stockert E., Aguet M., Old L.J., Schreiber R.D.
Demonstration of an interferon gamma-dependent tumor surveillance system in immunocompetent mice.
Proc. Natl. Acad. Sci. U.S.A. 95:7556-7561(1998)

PubMed=12794755; DOI=10.1002/ijc.11184
Endoh H., Yatabe Y., Shimizu S., Tajima K., Kuwano H., Takahashi T., Mitsudomi T.
RASSF1A gene inactivation in non-small cell lung cancer and its clinical implication.
Int. J. Cancer 106:45-51(2003)

Cross-references
Encyclopedic resources Wikidata; Q54953709
Polymorphism and mutation databases Cosmic; 1089233
IARC_TP53; 18799
Entry history
Entry creation04-Apr-2012
Last entry update21-Mar-2023
Version number19