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Cellosaurus HLC-1 (CVCL_5529)

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Cell line name HLC-1
Synonyms HLC1
Accession CVCL_5529
Resource Identification Initiative To cite this cell line use: HLC-1 (RRID:CVCL_5529)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Doubling time: ~33 hours, at 29th passage (PubMed=140093).
Caution: Indicated by Riken to originate from Okabe T. but with no reference provided. Therefore it is not certain that HLC-1 from Riken and HLC-1 originating from Akagi T. and Kimoto T. (PubMed=140093) are identical.
Genome ancestry Source: PubMed=30894373

Origin% genome
Native American0
East Asian, North90.08
East Asian, South3.53
South Asian0
European, North0
European, South2.02
Disease Lung adenocarcinoma (NCIt: C3512)
Derived from metastatic site: Pleural effusion.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_4Y14 (HLC-1-Luc)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): RCB


Run an STR similarity search on this cell line

PubMed=140093; DOI=10.20772/cancersci1959.67.4_483
Akagi T., Kimoto T.
Establishment and characteristics of a human lung adenocarcinoma cell line.
Gann 67:483-492(1976)

PubMed=3518877; DOI=10.3109/07357908609038260
Fogh J.
Human tumor lines for cancer research.
Cancer Invest. 4:157-184(1986)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3
Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. III, Barretina J., Gelfand E.T., Bielski C.M., Li H., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

Cell line collections RCB; RCB0083
Cell line databases/resources CCLE; HLC1_LUNG
DepMap; ACH-001088
Ontologies CLO; CLO_0050024
Biological sample resources BioSample; SAMN03472335
Chemistry resources PharmacoDB; HLC1_547_2019
Gene expression databases GEO; GSM784262
Other Wikidata; Q54889842
Polymorphism and mutation databases Cosmic; 1154601
Entry history
Entry creation04-Apr-2012
Last entry update06-Sep-2019
Version number17