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Cellosaurus IOSE-80 (CVCL_5546)

Cell line name IOSE-80
Synonyms IOSE 80; IOSE80; NFHIOSE-80; IOSE80UBC; IOSE-Van; IOSE-VAN
Accession CVCL_5546
Resource Identification Initiative To cite this cell line use: IOSE-80 (RRID:CVCL_5546)
Comments From: Canadian Ovarian Tissue Bank, University of British Columbia; Vancouver; Canada.
Doubling time: 26.2 hours (PubMed=10329039).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Ovary, surface epithelium; UBERON=UBERON_0001304.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_5547 (IOSE-80PC)CVCL_5548 (IOSE-80RZ)CVCL_2G68 (T80)
Sex of cell Female
Age at sampling Age unspecified
Category Transformed cell line
Publications

PubMed=1326894; DOI=10.1016/S0002-9378(11)91579-8
Maines-Bandiera S.L., Kruk P.A., Auersperg N.
Simian virus 40-transformed human ovarian surface epithelial cells escape normal growth controls but retain morphogenetic responses to extracellular matrix.
Am. J. Obstet. Gynecol. 167:729-735(1992)

PubMed=7967506
Auersperg N., Maines-Bandiera S.L., Dyck H.G., Kruk P.A.
Characterization of cultured human ovarian surface epithelial cells: phenotypic plasticity and premalignant changes.
Lab. Invest. 71:510-518(1994)

PubMed=10329039; DOI=10.1006/gyno.1999.5348
Kruk P.A., Godwin A.K., Hamilton T.C., Auersperg N.
Telomeric instability and reduced proliferative potential in ovarian surface epithelial cells from women with a family history of ovarian cancer.
Gynecol. Oncol. 73:229-236(1999)

DOI=10.5282/edoc.3898
Euer N.I.
Identification of target genes for the therapy and diagnosis of ovarian carcinoma.
Thesis PhD (2005), Ludwig Maximilians University of Munich, Germany

PubMed=15706405; DOI=10.3892/or.13.3.375
Euer N.I., Kaul S., Deissler H., Mobus V.J., Zeillinger R., Weidle U.H.
Identification of L1CAM, Jagged2 and neuromedin U as ovarian cancer-associated antigens.
Oncol. Rep. 13:375-387(2005)

PubMed=15947112; DOI=10.1677/erc.1.00896
Choi J.-H., Choi K.-C., Auersperg N., Leung P.C.K.
Gonadotropins upregulate the epidermal growth factor receptor through activation of mitogen-activated protein kinases and phosphatidyl-inositol-3-kinase in human ovarian surface epithelial cells.
Endocr. Relat. Cancer 12:407-421(2005)

PubMed=19926575; DOI=10.1309/AJCPTK87EMMIKPFS
DeRycke M.S., Andersen J.D., Harrington K.M., Pambuccian S.E., Kalloger S.E., Boylan K.L.M., Argenta P.A., Skubitz A.P.N.
S100A1 expression in ovarian and endometrial endometrioid carcinomas is a prognostic indicator of relapse-free survival.
Am. J. Clin. Pathol. 132:846-856(2009)

PubMed=23415752; DOI=10.1016/j.molonc.2012.12.007
Stordal B., Timms K., Farrelly A., Gallagher D., Busschots S., Renaud M., Thery J., Williams D., Potter J., Tran T., Korpanty G., Cremona M., Carey M.S., Li J., Li Y., Aslan O., O'Leary J.J., Mills G.B., Hennessy B.T.
BRCA1/2 mutation analysis in 41 ovarian cell lines reveals only one functionally deleterious BRCA1 mutation.
Mol. Oncol. 7:567-579(2013)

Cross-references
Cell line databases/resources Lonza; 13
Encyclopedic resources Wikidata; Q54897904
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number17