ID   MCF-10A-neoT
AC   CVCL_5554
SY   MCF-10A neoT; MCF-10AneoT; MCF10AneoT; MCF10-AneoT
DR   BTO; BTO:0005127
DR   ChEMBL-Cells; CHEMBL4295460
DR   ChEMBL-Targets; CHEMBL4296464
DR   PubChem_Cell_line; CVCL_5554
DR   Wikidata; Q54904297
RX   PubMed=1885681;
RX   PubMed=2009132;
RX   PubMed=11261825;
CC   Sequence variation: Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Gene deletion; HGNC; 1788; CDKN2B; Zygosity=Homozygous (from parent cell line).
CC   Transfected with: HGNC; 5173; HRAS (with p.Gly12Val).
CC   Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
CC   Derived from site: In situ; Breast, epithelium; UBERON=UBERON_0008359.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0598 ! MCF-10A
SX   Female
AG   36Y
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 29-06-23; Version: 17
//
RX   PubMed=1885681; DOI=10.1242/jcs.99.2.453;
RA   Russo J., Tait L., Russo I.H.;
RT   "Morphological expression of cell transformation induced by c-Ha-ras
RT   oncogene in human breast epithelial cells.";
RL   J. Cell Sci. 99:453-463(1991).
//
RX   PubMed=2009132; DOI=10.1002/mc.2940040106;
RA   Basolo F., Elliott J., Tait L., Chen X.-Q., Maloney T.M., Russo I.H.,
RA   Pauley R.J., Momiki S., Caamano J., Klein-Szanto A.J.P., Koszalka M.,
RA   Russo J.;
RT   "Transformation of human breast epithelial cells by c-Ha-ras
RT   oncogene.";
RL   Mol. Carcinog. 4:25-35(1991).
//
RX   PubMed=11261825; DOI=10.1023/A:1006461422273;
RA   Santner S.J., Dawson P.J., Tait L., Soule H.D., Eliason J.F.,
RA   Mohamed A.N., Wolman S.R., Heppner G.H., Miller F.R.;
RT   "Malignant MCF10CA1 cell lines derived from premalignant human breast
RT   epithelial MCF10AT cells.";
RL   Breast Cancer Res. Treat. 65:101-110(2001).
//