ID   XTC-2
AC   CVCL_5610
SY   LSTM-XL-2; XTC-YF; XTC; Xenopus Tadpole Carcass-2
DR   CLO; CLO_0050158
DR   Kerafast; EMU029
DR   RCB; RCB0771
DR   Wikidata; Q54995074
RX   DOI=10.17037/PUBS.04656048;
RX   PubMed=1811155;
RX   PubMed=2318264;
RX   PubMed=4708349;
RX   PubMed=8052658;
RX   PubMed=33389257;
WW   http://wiki.xenbase.org/xenwiki/index.php/tissue_culture_of_Xenopus_cell_lines_S3,_XTC_(Stukenberg_lab)
CC   Group: Amphibian cell line.
CC   Virology: Not susceptible to infection by SARS coronavirus 2 (SARS-CoV-2) (COVID-19) (PubMed=33389257).
CC   Doubling time: ~24 hours (DOI=10.17037/PUBS.04656048).
CC   Karyotypic information: Diploid karyotype (PubMed=4708349).
CC   Caution: According to RCB RCB0771 XTC-YF and XTC-2 are identical.
CC   Cell type: Fibroblast; CL=CL_0000057.
OX   NCBI_TaxID=8355; ! Xenopus laevis (African clawed frog)
SX   Sex unspecified
AG   Tadpole stage
CA   Spontaneously immortalized cell line
DT   Created: 04-04-12; Last updated: 29-06-23; Version: 14
//
RX   DOI=10.17037/PUBS.04656048;
RA   Leake C.J.;
RT   "Comparative studies on the infection of invertebrate and vertebrate
RT   cell lines with some arboviruses.";
RL   Thesis PhD (1977), London School of Hygiene and Tropical Medicine, United Kingdom.
//
RX   PubMed=1811155; DOI=10.1016/S0091-679X(08)60300-3;
RA   Smith J.C., Tata J.R.;
RT   "Xenopus cell lines.";
RL   Methods Cell Biol. 36:635-654(1991).
//
RX   PubMed=2318264; DOI=10.1016/0014-4827(90)90083-M;
RA   Snoek G.T., Koster C.H., de Laat S.W., Heideveld M., Durston A.J.,
RA   van Zoelen E.J.J.;
RT   "Effects of cell heterogeneity on production of polypeptide growth
RT   factors and mesoderm-inducing activity by Xenopus laevis XTC cells.";
RL   Exp. Cell Res. 187:203-210(1990).
//
RX   PubMed=4708349; DOI=10.1007/BF01926785;
RA   Pudney M., Varma M.G.R., Leake C.J.;
RT   "Establishment of a cell line (XTC-2) from the South African clawed
RT   toad, Xenopus laevis.";
RL   Experientia 29:466-467(1973).
//
RX   PubMed=8052658; DOI=10.1073/pnas.91.16.7767;
RA   St Germain D.L., Schwartzman R.A., Croteau W., Kanamori A., Wang Z.,
RA   Brown D.D., Galton V.A.;
RT   "A thyroid hormone-regulated gene in Xenopus laevis encodes a type III
RT   iodothyronine 5-deiodinase.";
RL   Proc. Natl. Acad. Sci. U.S.A. 91:7767-7771(1994).
//
RX   PubMed=33389257; DOI=10.1007/s10096-020-04106-0;
RA   Wurtz N., Penant G., Jardot P., Duclos N., La Scola B.;
RT   "Culture of SARS-CoV-2 in a panel of laboratory cell lines,
RT   permissivity, and differences in growth profile.";
RL   Eur. J. Clin. Microbiol. Infect. Dis. 40:477-484(2021).
//