ID   ZR-75-9a1
AC   CVCL_5613
DR   cancercelllines; CVCL_5613
DR   Wikidata; Q54996121
RX   PubMed=2713239;
CC   Population: Caucasian.
CC   Selected for resistance to: ChEBI; CHEBI:41774; Tamoxifen.
CC   Sequence variation: Mutation; HGNC; 5173; HRAS; Simple; p.Glu162Lys (c.484G>A); ClinVar=VCV001034833; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 9588; PTEN; Simple; p.Leu108Arg (c.323T>G); Zygosity=Homozygous (from parent cell line).
CC   Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
DI   NCIt; C4194; Invasive breast carcinoma of no special type
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0588 ! ZR-75-1
SX   Female
AG   63Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 05-10-23; Version: 18
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RX   PubMed=2713239; DOI=10.1038/bjc.1989.107;
RA   van den Berg H.W., Lynch M., Martin J., Nelson J., Dickson G.R.,
RA   Crockard A.D.;
RT   "Characterisation of a tamoxifen-resistant variant of the ZR-75-1
RT   human breast cancer cell line (ZR-75-9a1) and ability of the resistant
RT   phenotype.";
RL   Br. J. Cancer 59:522-526(1989).
//