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Cellosaurus MNT-1 (CVCL_5624)

Cell line name MNT-1
Synonyms MNT1; MNT
Accession CVCL_5624
Resource Identification Initiative To cite this cell line use: MNT-1 (RRID:CVCL_5624)
Comments Characteristics: Highly pigmented.
Virology: Susceptible to infection by human metapneumovirus (MNPV) (PubMed=28940687).
Omics: Exosome proteome analysis.
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000027.
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_5625 ! MNT-3
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): ATCC

Markers:
AmelogeninX
CSF1PO10
D5S81813
D7S8209
D13S31711
D16S53910
TH016,9
TPOX8,10
vWA16,18

Run an STR similarity search on this cell line
Web pages https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/m/cell-lines-detail-545.html
Publications

PubMed=1701342
Nistico P., Tecce R., Giacomini P., Cavallari A., D'Agnano I., Fisher P.B., Natali P.G.
Effect of recombinant human leukocyte, fibroblast, and immune interferons on expression of class I and II major histocompatibility complex and invariant chain in early passage human melanoma cells.
Cancer Res. 50:7422-7429(1990)

PubMed=1706743; DOI=10.1111/1523-1747.ep12470092
Cuomo M., Nicotra M.R., Apollonj C., Fraioli R., Giacomini P., Natali P.G.
Production and characterization of the murine monoclonal antibody 2G10 to a human T4-tyrosinase epitope.
J. Invest. Dermatol. 96:446-451(1991)

PubMed=11266471; DOI=10.1083/jcb.152.4.809
Raposo G., Tenza D., Murphy D.M., Berson J.F., Marks M.S.
Distinct protein sorting and localization to premelanosomes, melanosomes, and lysosomes in pigmented melanocytic cells.
J. Cell Biol. 152:809-824(2001)

PubMed=12417263; DOI=10.1016/S0006-2952(02)01353-9
De Marco F., Perluigi M., Marcante M.L., Coccia R., Foppoli C., Blarzino C., Rosei M.A.
Cytotoxicity of dopamine-derived tetrahydroisoquinolines on melanoma cells.
Biochem. Pharmacol. 64:1503-1512(2002)

PubMed=25950383; DOI=10.1111/pcmr.12380
Lazar I., Clement E., Ducoux-Petit M., Denat L., Soldan V., Dauvillier S., Balor S., Burlet-Schiltz O., Larue L., Muller C., Nieto L.
Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines.
Pigment Cell Melanoma Res. 28:464-475(2015)

PubMed=28940687; DOI=10.1111/1348-0421.12542
Sato K., Watanabe O., Ohmiya S., Chiba F., Suzuki A., Okamoto M., Younghuang J., Hata A., Nonaka H., Kitaoka S., Nagai Y., Kawamura K., Hayashi M., Kumaki S., Suzuki T., Kawakami K., Nishimura H.
Efficient isolation of human metapneumovirus using MNT-1, a human malignant melanoma cell line with early and distinct cytopathic effects.
Microbiol. Immunol. 61:497-506(2017)

Cross-references
Cell line collections (Providers) ATCC; CRL-3450
Anatomy/cell type resources BTO; BTO:0002946
Encyclopedic resources Wikidata; Q54906273
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number14