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Cellosaurus NALM-25 (CVCL_5664)

[Text version]
Cell line name NALM-25
Synonyms NALM25
Accession CVCL_5664
Resource Identification Initiative To cite this cell line use: NALM-25 (RRID:CVCL_5664)
Comments Population: Japanese.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Gene fusion; HGNC; 76; ABL1 + HGNC; 1014; BCR; Name(s)=BCR-ABL1, BCR-ABL (PubMed=1667895; PubMed=10071072).
Disease Adult B acute lymphoblastic leukemia with t(9;22)(q34.1;q11.2) BCR-ABL1 (NCIt: C114819)
B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2) (ORDO: Orphanet_585909)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_QX01 ! B262
CVCL_3888 ! NALM-24
Sex of cell Female
Age at sampling 42Y
Category Cancer cell line
STR profile Source(s): JCRB

Markers:
AmelogeninX
CSF1PO10
D5S81810
D7S82012,13
D13S3178,10
D16S5399,11
TH017,9
TPOX11,12
vWA14

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Publications

PubMed=1667895
Matsuo Y., Ariyasu T., Adachi T., Tsubota T., Minowada J.
Two t(9;22) leukemia cell lines (NALM-24 and NALM-25) with bi-phenotypic characteristics and an EBV-positive B-cell non-leukemia cell line (B262) established from a patient with acute lymphoblastic leukemia.
Hum. Cell 4:339-342(1991)

PubMed=9680106; DOI=10.1016/S0145-2126(98)00050-2
Matsuo Y., Drexler H.G.
Establishment and characterization of human B cell precursor-leukemia cell lines.
Leuk. Res. 22:567-579(1998)

PubMed=10071072; DOI=10.1016/s0145-2126(98)00171-4
Drexler H.G., MacLeod R.A.F., Uphoff C.C.
Leukemia cell lines: in vitro models for the study of Philadelphia chromosome-positive leukemia.
Leuk. Res. 23:207-215(1999)

Cross-references
Cell line collections (Providers) JCRB; JCRB1828
Encyclopedic resources Wikidata; Q54907407
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number17