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Cellosaurus CERV-186 (CVCL_5720)

[Text version]
Cell line name CERV-186
Synonyms Cerv-186; MRI-H-186; MRI-H186
Accession CVCL_5720
Resource Identification Initiative To cite this cell line use: CERV-186 (RRID:CVCL_5720)
Comments Virology: Contains around 26 copies of the HPV16 genome; some complete and others truncated.
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related cervical squamous cell carcinoma (NCIt: C27676)
Squamous cell carcinoma of the cervix uteri (ORDO: Orphanet_213767)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 42Y
Category Cancer cell line
STR profile Source(s): CLS

Markers:
AmelogeninX
CSF1PO9,11
D3S135815,18
D5S81811,12
D7S8208,12
D8S117914
D13S31712
D16S53913
D18S5116
D21S1129,30
FGA19,20
Penta D10,12
Penta E5,7
TH016
TPOX8,11
vWA14,17

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Publications

PubMed=15531914; DOI=10.1038/sj.onc.1208235
Baldus S.E., Schwarz E., Lohrey C., Zapatka M., Landsberg S., Hahn S.A., Schmidt D., Dienes H.-P., Schmiegel W.H., Schwarte-Waldhoff I.
Smad4 deficiency in cervical carcinoma cells.
Oncogene 24:810-819(2005)

PubMed=21439369; DOI=10.1016/j.mcp.2011.03.003
Schmitt M., Pawlita M.
The HPV transcriptome in HPV16 positive cell lines.
Mol. Cell. Probes 25:108-113(2011)

Cross-references
Cell line collections (Providers) CLS; 300290
Encyclopedic resources Wikidata; Q54809320
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number17