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Cellosaurus CH-157MN (CVCL_5723)

[Text version]

Cell line name CH-157MN
Synonyms CH157-MN; CH-157-MN; CH-157 MN; CH157MN
Accession CVCL_5723
Resource Identification Initiative To cite this cell line use: CH-157MN (RRID:CVCL_5723)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Doubling time: 22 hours (PubMed=25984343).
Omics: Deep exome analysis.
Omics: shRNA library screening.
Sequence variations NRAS p.Gln61Lys (c.181C>A) (DepMap).
Genome ancestry Source: PubMed=30894373

Origin% genome
African0.5
Native American0
East Asian, North2.54
East Asian, South0
South Asian0.15
European, North57.82
European, South38.99
Disease Meningioma (NCIt: C3230)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_HA68 (CH-157MN-LucNeo)
Sex of cell Female
Age at sampling 59Y
Category Cancer cell line
Publications

PubMed=7714613; DOI=10.3171/jns.1995.82.5.0864
Tsai J.-C., Goldman C.K., Gillespie G.Y.
Vascular endothelial growth factor in human glioma cell lines: induced secretion by EGF, PDGF-BB, and bFGF.
J. Neurosurg. 82:864-873(1995)

PubMed=10083766
Tsai J.-C., Hsiao Y.-Y., Teng L.-J., Shun C.-T., Chen C.-T., Goldman C.K., Kao M.-C.
Regulation of vascular endothelial growth factor secretion in human meningioma cells.
J. Formos. Med. Assoc. 98:111-117(1999)

PubMed=18261772; DOI=10.1016/j.surneu.2007.06.031
Ragel B.T., Couldwell W.T., Gillespie D.L., Wendland M.M., Whang K., Jensen R.L.
A comparison of the cell lines used in meningioma research.
Surg. Neurol. 70:295-307(2008)

PubMed=25984343; DOI=10.1038/sdata.2014.35
Cowley G.S., Weir B.A., Vazquez F., Tamayo P., Scott J.A., Rusin S., East-Seletsky A., Ali L.D., Gerath W.F.J., Pantel S.E., Lizotte P.H., Jiang G., Hsiao J., Tsherniak A., Dwinell E., Aoyama S., Okamoto M., Harrington W., Gelfand E., Green T.M., Tomko M.J., Gopal S., Wong T.C., Li H., Howell S., Stransky N., Liefeld T., Jang D., Bistline J., Hill Meyers B., Armstrong S.A., Anderson K.C., Stegmaier K., Reich M., Pellman D., Boehm J.S., Mesirov J.P., Golub T.R., Root D.E., Hahn W.C.
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies.
Sci. Data 1:140035-140035(2014)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3
Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. III, Barretina J., Gelfand E.T., Bielski C.M., Li H., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

Cross-references
Cell line databases/resources CCLE; CH157MN_CENTRAL_NERVOUS_SYSTEM
Cell_Model_Passport; SIDM01543
DepMap; ACH-000025
Biological sample resources BioSample; SAMN10988423
Other Wikidata; Q54811594
Polymorphism and mutation databases Cosmic; 2516046
Entry history
Entry creation04-Apr-2012
Last entry updated05-Jul-2019
Version number11