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Cellosaurus PDV (CVCL_5858)

Cell line name PDV
Accession CVCL_5858
Resource Identification Initiative To cite this cell line use: PDV (RRID:CVCL_5858)
Comments Transformant: ChEBI; CHEBI:59032; 7,12-dimethyltetraphene (DMBA; dimethylbenzanthracene).
Derived from site: In situ; Skin, epidermis; UBERON=UBERON_0001003.
Cell type: Keratinocyte; CL=CL_0000312.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/10 LP.
Hierarchy Children:
CVCL_4271 (PDVC 57B)
Sex of cell Sex unspecified
Age at sampling <1D
Category Transformed cell line
Publications

PubMed=102384
Fusenig N.E., Amer S.M., Boukamp P., Worst P.K.M.
Characteristics of chemically transformed mouse epidermal cells in vitro and in vivo.
Bull. Cancer 65:271-279(1978)

PubMed=6190961; DOI=10.1111/1523-1747.ep12541032
Fusenig N.E., Breitkreutz D., Dzarlieva-Petrusevska R.T., Boukamp P., Bohnert A., Tilgen W.
Growth and differentiation characteristics of transformed keratinocytes from mouse and human skin in vitro and in vivo.
J. Invest. Dermatol. 81:168s-175s(1983)

PubMed=2414007
Fusenig N.E., Dzarlieva-Petrusevska R.T., Breitkreutz D.
Phenotypic and cytogenetic characteristics of different stages during spontaneous transformation of mouse keratinocytes in vitro.
Carcinog. Compr. Surv. 9:293-326(1985)

PubMed=2185890; DOI=10.1016/0092-8674(90)90523-H
Bremner R., Balmain A.
Genetic changes in skin tumor progression: correlation between presence of a mutant ras gene and loss of heterozygosity on mouse chromosome 7.
Cell 61:407-417(1990)

PubMed=1855225
Buchmann A., Ruggeri B., Klein-Szanto A.J.P., Balmain A.
Progression of squamous carcinoma cells to spindle carcinomas of mouse skin is associated with an imbalance of H-ras alleles on chromosome 7.
Cancer Res. 51:4097-4101(1991)

PubMed=1934268; DOI=10.1093/carcin/12.10.1875
Quintanilla M., Haddow S., Jonas D., Jaffe D., Bowden G.T., Balmain A.
Comparison of ras activation during epidermal carcinogenesis in vitro and in vivo.
Carcinogenesis 12:1875-1881(1991)

PubMed=12807763; DOI=10.1093/carcin/bgg067
Zoumpourlis V., Solakidi S., Papathoma A., Papaevangeliou D.
Alterations in signal transduction pathways implicated in tumour progression during multistage mouse skin carcinogenesis.
Carcinogenesis 24:1159-1165(2003)

Cross-references
Cell line collections (Providers) CLS; 400314
Encyclopedic resources Wikidata; Q54946870
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number12