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Cellosaurus KTCTL-21 (CVCL_5868)

[Text version]

Cell line name KTCTL-21
Synonyms KTCTL21; RCC-AB; RCCAB
Accession CVCL_5868
Resource Identification Initiative To cite this cell line use: KTCTL-21 (RRID:CVCL_5868)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: Transcriptome analysis.
Genome ancestry Source: PubMed=30894373

Origin% genome
African0
Native American0.07
East Asian, North0.03
East Asian, South0
South Asian1.41
European, North62.87
European, South35.62
Disease Clear cell renal cell carcinoma (NCIt: C4033)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 49Y
Category Cancer cell line
STR profile Source(s): CLS; Cosmic-CLP

Markers:
AmelogeninX,Y
CSF1PO10,13
D3S135817
D5S81811,12
D7S8209,11
D8S117912,15
D13S31712,13
D16S53911
D18S5115
D21S1130,33.2
FGA22,25
Penta D10,12
Penta E7
TH017,9.3
TPOX8,11
vWA15,19

Run an STR similarity search on this cell line
Web pages http://www.xlbiotec.com/product.php?productid=40243
Publications

PubMed=8086765; DOI=10.1007/BF00252823
Gross A.J., Wolff M., Fandrey J., Miersch W.-D., Dieckmann K.-P., Jelkmann W.
Prevalence of paraneoplastic erythropoietin production by renal cell carcinomas.
Clin. Investig. 72:337-340(1994)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=28489074; DOI=10.1038/ncomms15165
Sinha R., Winer A.G., Chevinsky M., Jakubowski C., Chen Y.-B., Dong Y., Tickoo S.K., Reuter V.E., Russo P., Coleman J.A., Sander C., Hsieh J.J., Hakimi A.A.
Analysis of renal cancer cell lines from two major resources enables genomics-guided cell line selection.
Nat. Commun. 8:15165-15165(2017)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

Cross-references
Cell line collections CLS; 300247/NA
Cell line databases/resources CCLE; RCCAB_KIDNEY
Cell_Model_Passport; SIDM00821
Cosmic-CLP; 1524418
DepMap; ACH-002187
GDSC; 1524418
Gene expression databases ArrayExpress; E-MTAB-3610
GEO; GSM1670360
Other Wikidata; Q54900641
Polymorphism and mutation databases Cosmic; 1352059
Cosmic; 1751970
Entry history
Entry creation04-Apr-2012
Last entry updated05-Jul-2019
Version number16