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Cellosaurus KTCTL-13 (CVCL_5870)

[Text version]

Cell line name KTCTL-13
Synonyms KTCTL13; KTCTL 13; RCC-ER; RCCER
Accession CVCL_5870
Resource Identification Initiative To cite this cell line use: KTCTL-13 (RRID:CVCL_5870)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
Part of: MD Anderson Cell Lines Project.
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: Protein expression by reverse-phase protein arrays.
Omics: Transcriptome analysis.
Misspelling: KTCL13; In Cosmic 972923 and PubMed=7915601.
Disease Clear cell renal cell carcinoma (NCIt: C4033)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 57Y
Category Cancer cell line
STR profile Source(s): CLS; Cosmic-CLP

Markers:
AmelogeninX,Y
CSF1PO10,11
D3S135818
D5S81811
D7S82010,12
D8S117912,15
D13S31711,13
D16S5399,12
D18S5114,17
D21S1130,31.2
FGA21,26
Penta D10,12
Penta E11,12
TH016
TPOX8,11
vWA17,18

Run an STR similarity search on this cell line
Web pages http://tcpaportal.org/mclp/
Publications

PubMed=7915601; DOI=10.1038/ng0594-85
Gnarra J.R., Tory K., Weng Y., Schmidt L., Wei M.H., Li H., Latif F., Liu S., Chen F., Duh F.-M., Lubensky I.A., Duan D.R., Florence C., Pozzatti R., Walther M.M., Bander N.H., Grossman H.B., Brauch H., Pomer S., Brooks J.D., Isaacs W.B., Lerman M.I., Zbar B., Linehan W.M.
Mutations of the VHL tumour suppressor gene in renal carcinoma.
Nat. Genet. 7:85-90(1994)

PubMed=8086765; DOI=10.1007/BF00252823
Gross A.J., Wolff M., Fandrey J., Miersch W.-D., Dieckmann K.-P., Jelkmann W.
Prevalence of paraneoplastic erythropoietin production by renal cell carcinomas.
Clin. Investig. 72:337-340(1994)

PubMed=11929824
Batrla R., Linnebacher M., Rudy W., Stumm S., Wallwiener D., Guckel B.
CD40-expressing carcinoma cells induce down-regulation of CD40 ligand (CD154) and impair T-cell functions.
Cancer Res. 62:2052-2057(2002)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005
Li J., Zhao W., Akbani R., Liu W., Ju Z., Ling S., Vellano C.P., Roebuck P., Yu Q., Eterovic A.K., Byers L.A., Davies M.A., Deng W., Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D., Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y., Mills G.B., Liang H.
Characterization of human cancer cell lines by reverse-phase protein arrays.
Cancer Cell 31:225-239(2017)

PubMed=28489074; DOI=10.1038/ncomms15165
Sinha R., Winer A.G., Chevinsky M., Jakubowski C., Chen Y.-B., Dong Y., Tickoo S.K., Reuter V.E., Russo P., Coleman J.A., Sander C., Hsieh J.J., Hakimi A.A.
Analysis of renal cancer cell lines from two major resources enables genomics-guided cell line selection.
Nat. Commun. 8:15165-15165(2017)

Cross-references
Cell line collections CLS; 300238/p696_RCC-ER
Cell line databases/resources CCLE; RCCER_KIDNEY
Cell_Model_Passport; SIDM00820
Cosmic-CLP; 1524417
GDSC; 1524417
Gene expression databases ArrayExpress; E-MTAB-3610
GEO; GSM1670361
Other Wikidata; Q54900630
Polymorphism and mutation databases Cosmic; 972923
Cosmic; 1352060
Cosmic; 1751971