Home  |  Contact

Cellosaurus KTCTL-195 (CVCL_5880)

[Text version]

Cell line name KTCTL-195
Synonyms KTCTL195; RCC-JW; RCCJW
Accession CVCL_5880
Resource Identification Initiative To cite this cell line use: KTCTL-195 (RRID:CVCL_5880)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
Part of: MD Anderson Cell Lines Project.
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: Protein expression by reverse-phase protein arrays.
Omics: Transcriptome analysis.
Genome ancestry Source: PubMed=30894373

Origin% genome
African0
Native American1.71
East Asian, North0
East Asian, South0
South Asian1.93
European, North62.95
European, South33.4
Disease Clear cell renal cell carcinoma (NCIt: C4033)
Clear cell renal carcinoma (ORDO: Orphanet_319276)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 46Y
Category Cancer cell line
STR profile Source(s): CLS; Cosmic-CLP

Markers:
AmelogeninX,Y
CSF1PO10,11
D3S135816
D5S81811,12
D7S8208,11
D8S117913
D13S3178,12
D16S53910,11
D18S5116
D21S1128,30
FGA22
Penta D12,13
Penta E7
TH016,8
TPOX8
vWA17,18

Run an STR similarity search on this cell line
Web pages http://tcpaportal.org/mclp/
Publications

PubMed=11762795; DOI=10.1007/s002400100214
Siebels M., Meyer G., Habicht A., Meuer S.C., Moebius U.
Simultaneous ligation of CD5 and CD28 with monoclonal antibodies restores impaired immunostimulatory function in human renal cell carcinoma.
Urol. Res. 29:330-337(2001)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005
Li J., Zhao W., Akbani R., Liu W., Ju Z., Ling S., Vellano C.P., Roebuck P., Yu Q., Eterovic A.K., Byers L.A., Davies M.A., Deng W., Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D., Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y., Mills G.B., Liang H.
Characterization of human cancer cell lines by reverse-phase protein arrays.
Cancer Cell 31:225-239(2017)

PubMed=28489074; DOI=10.1038/ncomms15165
Sinha R., Winer A.G., Chevinsky M., Jakubowski C., Chen Y.-B., Dong Y., Tickoo S.K., Reuter V.E., Russo P., Coleman J.A., Sander C., Hsieh J.J., Hakimi A.A.
Analysis of renal cancer cell lines from two major resources enables genomics-guided cell line selection.
Nat. Commun. 8:15165-15165(2017)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

Cross-references
Cell line collections CLS; 300244/p680_RCC-JW
Cell line databases/resources CCLE; RCCJW_KIDNEY
Cell_Model_Passport; SIDM00817
Cosmic-CLP; 1524416
DepMap; ACH-002191
Chemistry resources GDSC; 1524416
PharmacoDB; RCCJW_1291_2019
Gene expression databases ArrayExpress; E-MTAB-3610
GEO; GSM1670363
Other Wikidata; Q54900636
Polymorphism and mutation databases Cosmic; 1352064
Cosmic; 1751975
Entry history
Entry creation04-Apr-2012
Last entry update12-Mar-2020
Version number19