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Cellosaurus J2E-NR (CVCL_5984)

[Text version]
Cell line name J2E-NR
Synonyms J2E-Non Responder
Accession CVCL_5984
Resource Identification Initiative To cite this cell line use: J2E-NR (RRID:CVCL_5984)
Comments Characteristics: Compared to the parent cell line, does not respond to EPO.
Transformant: Recombinant retrovirus J2.
Derived from site: In situ; Embryonic liver; UBERON=UBERON_0002107.
Cell type: Erythroblast; CL=CL_0000765.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: CBA.
Hierarchy Parent: CVCL_0355 (J2E)
Sex of cell Sex unspecified
Age at sampling 12FD
Category Transformed cell line
Publications

PubMed=1688637
Klinken S.P., Nicola N.A.
Evolution of a mutant J2E erythroid cell line which does not respond to erythropoietin.
Leukemia 4:24-28(1990)

PubMed=8631947; DOI=10.1074/jbc.271.7.3453
Tilbrook P.A., Bittorf T., Busfield S.J., Chappell D., Klinken S.P.
Disrupted signaling in a mutant J2E cell line that shows enhanced viability, but does not proliferate or differentiate, with erythropoietin.
J. Biol. Chem. 271:3453-3459(1996)

Cross-references
Encyclopedic resources Wikidata; Q54898465
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number10