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Cellosaurus JHU-011 (CVCL_5986)

Cell line name JHU-011
Synonyms JHU 011; JHU-011-SCC; JHU-O11; JHU011; HNSCC 011; O11; 011; 11
Accession CVCL_5986
Resource Identification Initiative To cite this cell line use: JHU-011 (RRID:CVCL_5986)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
Part of: MD Anderson Cell Lines Project.
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: Deep RNAseq analysis.
Omics: DNA methylation analysis.
Omics: Protein expression by reverse-phase protein arrays.
Omics: Transcriptome analysis.
Disease Laryngeal squamous cell carcinoma (NCIt: C4044)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 45Y
Category Cancer cell line
STR profile Source(s): ATCC; Cosmic-CLP; PubMed=21868764

Markers:
AmelogeninX
CSF1PO10,12
D13S31712
D16S5399,14
D5S8189,12
D7S82011
TH016,9
TPOX8,9
vWA16,17
Web pages http://tcpaportal.org/mclp/
Publications

PubMed=12925955; DOI=10.1002/ijc.11341
Minhas K.M., Singh B., Jiang W.W., Sidransky D., Califano J.A.
Spindle assembly checkpoint defects and chromosomal instability in head and neck squamous cell carcinoma.
Int. J. Cancer 107:46-52(2003)

PubMed=12963126; DOI=10.1016/S0304-3835(03)00344-6
Hoque M.O., Begum S., Sommer M., Lee T., Trink B., Ratovitski E., Sidransky D.
PUMA in head and neck cancer.
Cancer Lett. 199:75-81(2003)

PubMed=21868764; DOI=10.1158/1078-0432.CCR-11-0690
Zhao M., Sano D., Pickering C.R., Jasser S.A., Henderson Y.C., Clayman G.L., Sturgis E.M., Ow T.J., Lotan R., Carey T.E., Sacks P.G., Grandis J.R., Sidransky D., Heldin N.-E., Myers J.N.
Assembly and initial characterization of a panel of 85 genomically validated cell lines from diverse head and neck tumor sites.
Clin. Cancer Res. 17:7248-7264(2011)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005
Li J., Zhao W., Akbani R., Liu W., Ju Z., Ling S., Vellano C.P., Roebuck P., Yu Q., Eterovic A.K., Byers L.A., Davies M.A., Deng W., Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D., Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y., Mills G.B., Liang H.
Characterization of human cancer cell lines by reverse-phase protein arrays.
Cancer Cell 31:225-239(2017)

PubMed=29156801; DOI=10.18632/oncotarget.21174
Kalu N.N., Mazumdar T., Peng S., Shen L., Sambandam V., Rao X., Xi Y., Li L., Qi Y., Gleber-Netto F.O., Patel A., Wang J., Frederick M.J., Myers J.N., Pickering C.R., Johnson F.M.
Genomic characterization of human papillomavirus-positive and -negative human squamous cell cancer cell lines.
Oncotarget 8:86369-86383(2017)

Cross-references
Cell line collections ATCC; CRL-2719 - Discontinued
Cell line databases/resources CCLE; JHU011_UPPER_AERODIGESTIVE_TRACT
Cosmic-CLP; 1240161
GDSC; 1240161
Ontologies BTO; BTO:0003891
Biological sample resources BioSample; SAMN03471775
Gene expression databases ArrayExpress; E-MTAB-3610
GEO; GSM1669958
Other Wikidata; Q54898667