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Cellosaurus JHU-013 (CVCL_5988)

Cell line name JHU-013
Synonyms JHU 013; JHU013; JHU-O13; JHU-13; O13
Accession CVCL_5988
Resource Identification Initiative To cite this cell line use: JHU-013 (RRID:CVCL_5988)
Comments Problematic cell line: Contaminated. Shown to be a FaDu derivative (PubMed=21868764).
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00404.
Sequence variations Homozygous for CDKN2A c.151-1G>T; splice donor mutation (from parent cell line).
Heterozygous for TP53 p.Arg248Leu (c.743G>T) and c.376-1G>A (from parent cell line).
Disease Hypopharyngeal squamous cell carcinoma (NCIt: C4043)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1218 (FaDu)
Sex of cell Male
Age at sampling 56Y
Category Cancer cell line
STR profile Source(s): PubMed=21868764

Markers:
AmelogeninNot_detected
CSF1PO12
D5S81812
D7S82011,12
D13S3178,9
D16S53911
TH018
TPOX11
vWA15,17
Web pages http://iclac.org/wp-content/uploads/Cross-Contaminations_v9_distribution.xlsx
Publications

PubMed=12925955; DOI=10.1002/ijc.11341
Minhas K.M., Singh B., Jiang W.W., Sidransky D., Califano J.A.
Spindle assembly checkpoint defects and chromosomal instability in head and neck squamous cell carcinoma.
Int. J. Cancer 107:46-52(2003)

PubMed=12963126; DOI=10.1016/S0304-3835(03)00344-6
Hoque M.O., Begum S., Sommer M., Lee T., Trink B., Ratovitski E., Sidransky D.
PUMA in head and neck cancer.
Cancer Lett. 199:75-81(2003)

PubMed=21868764; DOI=10.1158/1078-0432.CCR-11-0690
Zhao M., Sano D., Pickering C.R., Jasser S.A., Henderson Y.C., Clayman G.L., Sturgis E.M., Ow T.J., Lotan R., Carey T.E., Sacks P.G., Grandis J.R., Sidransky D., Heldin N.-E., Myers J.N.
Assembly and initial characterization of a panel of 85 genomically validated cell lines from diverse head and neck tumor sites.
Clin. Cancer Res. 17:7248-7264(2011)

Cross-references
Cell line databases/resources GDSC; 1298152
Ontologies BTO; BTO:0003890
Biological sample resources BioSample; SAMN03151639
Other Wikidata; Q54898669
Polymorphism and mutation databases Cosmic; 1122670
Cosmic; 1530747