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Cellosaurus JHU-019 (CVCL_5989)

[Text version]

Cell line name JHU-019
Synonyms JHU 019; JHU-O19; JHU019; O19; 019; 19
Accession CVCL_5989
Resource Identification Initiative To cite this cell line use: JHU-019 (RRID:CVCL_5989)
Comments Problematic cell line: Contaminated. Shown to be a PC-3 derivative (PubMed=21868764). Originally thought to originate from a 58 year old female patient oropharyngeal squamous cell carcinoma.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00405.
Sequence variations Homozygous for TP53 p.Lys139fs*31 (c.413delC) (from parent cell line).
Disease Prostate carcinoma (NCIt: C4863)
Derived from metastatic site: Bone.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0035 (PC-3)
Sex of cell Male
Age at sampling 62Y
Category Cancer cell line
STR profile Source(s): ATCC; PubMed=21868764

Markers:
AmelogeninX
CSF1PO11
D5S8189,13 (ATCC)
13 (PubMed=21868764)
D7S8208,11
D13S31711
D16S53911
TH016,7
TPOX8,9
vWA17

Run an STR similarity search on this cell line
Web pages http://iclac.org/wp-content/uploads/Cross-Contaminations_v9_distribution.xlsx
Publications

PubMed=12925955; DOI=10.1002/ijc.11341
Minhas K.M., Singh B., Jiang W.W., Sidransky D., Califano J.A.
Spindle assembly checkpoint defects and chromosomal instability in head and neck squamous cell carcinoma.
Int. J. Cancer 107:46-52(2003)

PubMed=12963126; DOI=10.1016/S0304-3835(03)00344-6
Hoque M.O., Begum S., Sommer M., Lee T., Trink B., Ratovitski E., Sidransky D.
PUMA in head and neck cancer.
Cancer Lett. 199:75-81(2003)

PubMed=21868764; DOI=10.1158/1078-0432.CCR-11-0690
Zhao M., Sano D., Pickering C.R., Jasser S.A., Henderson Y.C., Clayman G.L., Sturgis E.M., Ow T.J., Lotan R., Carey T.E., Sacks P.G., Grandis J.R., Sidransky D., Heldin N.-E., Myers J.N.
Assembly and initial characterization of a panel of 85 genomically validated cell lines from diverse head and neck tumor sites.
Clin. Cancer Res. 17:7248-7264(2011)

Cross-references
Cell line collections ATCC; CRL-2721 - Discontinued
Ontologies BTO; BTO:0003889
Biological sample resources BioSample; SAMN03151893
BioSample; SAMN03471776
Chemistry resources PharmacoDB; JHU019_694_2019
Other Wikidata; Q54898670
Entry history
Entry creation04-Apr-2012
Last entry updated06-Sep-2019
Version number16